Sequence of DPV Lujo virus
Lujo virus segment L multifunctional matrix-like protein and large RNA-dependent RNA polymerase genes, complete cds.
ACC No: FJ952385
Dated: 2009-06-29 | Length: 7163 | CRC: -236587809
ID FJ952385; SV 1; linear; genomic RNA; STD; VRL; 7163 BP.
XX
AC FJ952385;
XX
DT 05-JUN-2009 (Rel. 101, Created)
DT 29-JUN-2009 (Rel. 101, Last updated, Version 2)
XX
DE Lujo virus segment L multifunctional matrix-like protein and large
DE RNA-dependent RNA polymerase genes, complete cds.
XX
KW .
XX
OS Lujo virus
OC Viruses; ssRNA negative-strand viruses; Arenaviridae; Arenavirus;
OC unclassified Arenaviridae.
XX
RN [1]
RC Publication Status: Online-Only
RP 1-7163
RX DOI; 10.1371/journal.ppat.1000455.
RX PUBMED; 19478873.
RA Briese T., Paweska J.T., McMullan L.K., Hutchison S.K., Street C.,
RA Palacios G., Khristova M.L., Weyer J., Swanepoel R., Egholm M.,
RA Nichol S.T., Lipkin W.I.;
RT "Genetic detection and characterization of Lujo virus, a new hemorrhagic
RT fever-associated arenavirus from southern Africa";
RL PLoS Pathog. 5(5):E1000455-E1000455(2009).
XX
RN [2]
RP 1-7163
RA Briese T., Lipkin W.I.;
RT ;
RL Submitted (22-APR-2009) to the EMBL/GenBank/DDBJ databases.
RL Center for Infection and Immunity, MSPH, Columbia University, 722 West,
RL 168th Street, New York, NY 10032, USA
XX
FH Key Location/Qualifiers
FH
FT source 1. .7163
FT /organism="Lujo virus"
FT /segment="L"
FT /host="Homo sapiens"
FT /mol_type="genomic RNA"
FT /country="South Africa:Zambia"
FT /collection_date="Oct-2008"
FT /db_xref="taxon:649188"
FT CDS 46. .333
FT /codon_start=1
FT /product="multifunctional matrix-like protein"
FT /note="Z"
FT /protein_id="ACR56361.1"
FT /translation="MGQRHSSGSGQPNPKPSDSDHEARRSELHSDASHLGPLNCKSCWK
FT SKKALVKCYDHYLCLNCLSLLMGITPRCPFCYRELPKNLDLAEAPSAPPL"
FT variation 375
FT /replace=""
FT variation 383
FT /replace=""
FT CDS complement(438. .7142)
FT /codon_start=1
FT /product="large RNA-dependent RNA polymerase"
FT /note="L; RdRp"
FT /protein_id="ACR56362.1"
FT /translation="MDSLKNELLQLISRNFPNDERLAPQKLKVLCQTEPKFIMIEGLKL
FT LSTCIEIDICDENGCIHNTEEKSVELILRENGFVVPSLPCVTPDGFKVSGNMLILLECF
FT VRLNPLEYEQKYNNDMKKLSSLRGDLEHSGITLVPLVVGRSGYENNSIPDWVVFKFKNL
FT IFRLLEYVQENEAMLEESEYIRLSESLKGNGSKLFDLDAFNLLKNNSGEHFENIMRLCV
FT EGVRPDIPLSEVNSKIVENFLEFKAKLKKGVIPPLFMMTDKERLLKEFCDLYLDQGVSS
FT APESKWELLRDFKEATSFTNFIYFDSKNDEGHPEQDKAEKVGNDRHYHRKSCGMISMLN
FT KSKSIKLMNTRRKLLLGLDVVRLSHLISLKNEFPRGDDDESVWCGQSFTTVSDRLVSVM
FT STQRDLKKHLFRLSRMPKNKSKGKTKALNEIFLDYRRLILNKVFNSLNAHGLTAHSYGL
FT EASDFENWPSLEDFMSFKKSGSIPVMNYERDNFRPQMHLDETSFSEDITDLRMISSLSL
FT SLVNSMKTSSVSKIRQNASGKNRYGRVSCEECFFQEIKSPKGTFTLIYQKTGESSKCYS
FT INRDGEHICSFYADPKRYFLPIMSSEVIKGVIDTMVQWLSDVKELEGCIDEIKILLKII
FT FMSVLLNPSKRSQKFLQNLRYFIMAFFGLAHHVDLMEKVKEDLITKSEYLIYRCVRKVM
FT ILVLGDSVETMLTSRFKFLLNLSYICHFITKETPDRVTDQIKCFEKFLEPKLKFKSVFV
FT NPKNDVTKEESSLLLESGSRFLNKDEFDVKAPGVSKQMLSLMLSFVNSTSGFTPDELAK
FT IKTNPLKDARCSTALDLSSNKSVVIPKTDDKGNSVDYDYDKLVGVSLCDIVEKFHNKTK
FT FCLSPEQLEYKILKSISHTMAEENRKEKKKKTTTRDSQTSVSESIDLEESEDSVPLEEL
FT LPSESLSKIRCSIDKIFSKYQHKQNPKKVQDTEGISVSEALRDLVANHRDRNLILSEVS
FT YHLVEDFEESLFPDSFYEDFCERVGNSPKYSKLVMTETVLESCPIEMFTKNITRKFYEE
FT GDWFKCFKTILLQLNVNHYSGRFKHNSRLRLNYKFDYKKLYEDARISERESNSEAMCKL
FT LSFTKCITSTLKNLCFYSDESPTSYNGAGPDTGRLQFSLSYKEQVGGNRELYIGDMKTK
FT MYTRFVEDFFESLTGQLNGSCLNDEAQFEEAISEMKQCIREGNLSYNMDHSKWGPTMCP
FT LLFLTVLKNIKYIKDFDKPIEHISTLLSWHVHKYVEVPFNVINAITKSFVKRQLGIQQG
FT VINTKTEEFIFSHLDHGIVPSHISSILDMGQGILHNASDYYGLITEKFINYTLKLLFRG
FT ELKSFTSSDDQISLFDKELSATLRDDTEELLCFLNYHYYLSSQLNKFVSPKSSLCEFVA
FT EFKSRFFVWGEEVPLLTKFVAASLHNVKCKTPHQLSETVDTIVDQCAANGVPINICNLL
FT QKRCINLLRYCRFPINPFLLNVNTDIKDWIDGTRGYRIQRQLENLFPDSTGTVRKLVRR
FT LYNSLKNDEVREDFLAELFSRDPFTVLKSLFKHYDLDEPQLRDCWLNLEAHHPIRMVLR
FT QKVLFPSALQIESVNLPTVIRVLQNKLSHSFTKSTQKLLSDSVNKSAFQSSVASGFIGL
FT AKTIGSKCVRDADRNCHYIVEILSKLESLPGLKVIMKDDILIVELESEDGSIQSDWPPE
FT CEWLRPMIRPILIDYLCIVLSNCLELGTWVLGDPEPPQRGPFLGRSSHDYVAVFPVKSA
FT VLEDKVGYNHILQSVRRLYPSLFETHLLPFLDDNSLRKSSWAPKIRFLDLCVSLDITCE
FT AISLISHVVKWKRSEQYTVLTLDLSNSHNRKFTTMIDSKVISTSDTCINFLKQLFFESL
FT IRPVLLSSRTLGSFTWFPHASMMPKGEGAPSLGPFENFVLKTIHKGQERPMYRDDLSSG
FT FSWIDLKDFKAYISSAHQRISRVSSADAGRDCFNLDERVVITITHNFIKRNRNGACDSK
FT FSIIHRIHGSVSDASEGFLMVEVLGVECGFSGAVRDEFVRTNILAIARSLSFSKEDMTV
FT FVQRQMIDQHEEPSNQDTIMVELIPGESFSVDDPLAYTRLGPDWVPVGLVLIDGDVKEL
FT KETVAQLKVSLDTKDVMIFLAELYPEHMALIKKGIETMLKKSQKHEVDLSRVDLIKCFK
FT DVGLTEHDLVDCFSGVIGWVKLSSYTLAYSKHLKDLVIAHPGGGMRLGGVCCRLLREGT
FT STIEIE"
XX
SQ Sequence 7163 BP; 2030 A; 1622 C; 1316 G; 2195 T; 0 other;
fj952385 Length: 7163 29-JUN-2009 Type: N Check: 7552 ..
1 gttaattgga ctacttttct agtacctcac ttcagtgaga gtgacatggg
51 tcagagacat tcctctggct ccggccaacc caaccccaag ccgagtgaca
101 gcgatcatga agcgagaagg tcagagcttc actcggacgc ctcccatctc
151 ggacctctga actgcaaatc ttgctggaag tcaaagaagg cactggtgaa
201 gtgctatgat cactacctct gtctaaactg cttaagcctt ctaatgggca
251 tcaccccaag atgtcccttc tgttacagag agctacccaa aaatctggac
301 cttgcagagg caccaagcgc accacccctc tgaagacccg cagcgaaacc
351 caaccaaggg gcgcccccct ctcgcggggg gggcgcagct ccgccgtcgc
401 gcgctccaca gaccacacca atcatcgatg cagaagatca ttcaatctca
451 atagtggatg tcccctctct caatagtcta cagcatactc caccaagtct
501 cattccacca ccaggatgag caatcaccag atccttgaga tgcttgctgt
551 acgctaatgt gtaggaactg agcttgaccc atccgattac ccctgagaaa
601 cagtccacca aatcatgctc cgttaggccc acatctttga aacacttgat
651 taggtccacc ctagacaaat caacctcatg tttttgagac tttttcagca
701 ttgtctctat ccctttcttt attaaagcca tgtgctctgg gtatagctca
751 gccaagaata tcataacatc tttagtatca agactgactt ttagctgtgc
801 aactgtctct ttcagctctt tcacatcacc atcaattaag acaaggccta
851 ccggaaccca gtctggccca aggcgtgtat aagcaagtgg gtcatcaaca
901 gagaaggact ccccaggaat cagttcaacc atgatggtat cctggtttga
951 tggctcttca tgctgatcaa tcatctgtct ctggacaaac actgtcatgt
1001 cttctttgct aaatgagagg ctcctagcaa tggccaagat attggtcctc
1051 acaaactcgt ccctcacagc tccagaaaat ccacactcaa cacccaggac
1101 ctccaccatc aggaagccct cagacgcatc gctgacactg ccgtgaattc
1151 tgtgaatgat actaaatttg ctgtcacagg ctccgtttct atttctttta
1201 ataaaattgt gagtgattgt tatgacgact ctctcatcaa gattaaaaca
1251 gtctctccct gcatcagcag aagacactct agatattctt tgatgagccg
1301 aagagatgta cgccttaaaa tccttaaggt caatccagct aaatccacta
1351 cttagatcat ccctgtacat tggcctctcc tggcctttgt ggattgtttt
1401 cagaacaaaa ttctcgaatg ggcccaaaga aggtgcaccc tcaccctttg
1451 gcatcatgga ggcatgtggg aaccatgtga atgaacctaa tgttctgctg
1501 gacagcaaca ctggcctaat cagagactcg aagaacaatt gctttaagaa
1551 attgatacat gtatcagatg tactgatcac ttttgaatca atcatagtcg
1601 tgaattttct attatgacta ttcgagaggt ctaaagtgag aactgtgtac
1651 tgctcagacc tcttccattt aacgacatga ctgataagac tgatagcttc
1701 acaagtgatg tcaagtgaga cacatagatc tagaaatctg atcttaggag
1751 cccaagaaga ctttctcaat gagttgtcgt ccagaaacgg aaggaggtga
1801 gtttcaaaaa gcgatggata taatcgtctt acactctgta aaatatgatt
1851 gtaacccact ttgtcttcca agacagcact tttgacaggg aacacagcaa
1901 catagtcatg gctagatctg cctaaaaatg ggcccctttg tggaggttca
1951 gggtccccta gtacccatgt ccccaactct agacaattgg acaatacaat
2001 gcatagataa tctatcaaaa ttggtcttat cattggtctt aaccattcgc
2051 actctggagg ccagtcagac tgaattgagc cgtcctctga ctccaattcc
2101 actatgagaa tgtcatcctt catgatgact tttaaaccag gcagtgattc
2151 cagttttgat aagatctcta ctatgtaatg acagttcctg tcagcatctc
2201 tcacacactt acttcctatc gtctttgcta gcccaataaa ccctgaagca
2251 acactgcttt ggaatgcact tttgttcact gaatctgata acagcttttg
2301 ggtgcttttt gtgaagctat ggcttaattt gttttgcagc accctgatca
2351 cagttggtag gttgactgat tctatctgaa gtgcagaagg aaagagaact
2401 ttctgacgaa gaaccattct gatggggtga tgtgcttcaa ggttcaacca
2451 gcagtctctc aattggggct catcaaggtc ataatgtttg aatagggact
2501 ttaggacagt gaatgggtct cttgagaaca actcagccaa aaagtcttcc
2551 ctcacctcat cattttttaa ggagttatac aatctcctta ctaactttcg
2601 aacagtccca gtgctatctg gaaataagtt ttctaactgt ctttgaatcc
2651 tgtaacctct ggttccatca atccaatctt tgatgtctgt attcacattg
2701 agcaagaatg gattaatagg gaatctacaa tacctcaata agttaataca
2751 tctcttttgc agaaggttgc atatgttaat tggcacccca tttgcagcgc
2801 attgatccac aatggtgtcc acagtttctg acagttgatg cggtgttttg
2851 cattttacat tgtgtaatga agctgctacg aactttgtta acaaagggac
2901 ctcttcaccc caaacaaaga atcttgactt aaattctgca acgaactcac
2951 agagcgagct tttgggactg acaaacttat taagctgact agataaataa
3001 tagtggtagt tcaaaaagca taggagctct tcagtgtcat cccttagtgt
3051 ggctgataat tctttgtcaa acaatgatat ttgatcatcg ctagaagtga
3101 aactcttcag ctcacctctg aacaaaagct tcagtgtgta gtttatgaac
3151 ttctcagtta ttaaaccata ataatcagat gcgttatgca atataccctg
3201 acccatgtct aagatgctgc taatgtgaga cggaacaata ccatgatcta
3251 aatgagaaaa gatgaactct tctgtttttg tgttaatgac accctgttgt
3301 atacctaact gacgttttac aaaggatttg gtaatggcat tgatgacgtt
3351 gaagggaacc tcaacatatt tatgaacatg ccaggacagt aatgttgaga
3401 tatgctcaat tggcttatca aaatctttaa tgtacttgat attttttaaa
3451 actgtcaaga agagaagcgg acacatagtt gggccccact tgctgtgatc
3501 catgttgtag ctaagattcc cttctctaat gcactgcttc atctctgaga
3551 ttgcctcctc aaactgtgct tcatcgttta agcagctccc atttagctga
3601 ccagtgagag actcaaaaaa gtcttccaca aaccttgtgt acatcttagt
3651 cttcatgtca ccgatgtaca attctctatt cccaccaacc tgttccttgt
3701 atgataaaga gaactggagc ctacccgtgt ctggaccagc accattgtag
3751 gaggtgggtg actcatctga atagaaacac aagtttttca gagtggacgt
3801 aatgcattta gtgaaagaca gcagtttaca catagcctca gaattactct
3851 ctctttcact tatcctggca tcttcgtaga gttttttgta atcaaactta
3901 taattaagtc ttagtctgga attgtgcttg aatctaccag agtagtgatt
3951 cacatttagt tgcaataaga tggtcttaaa gcatttgaac caatctccct
4001 cttcataaaa ctttcttgtg atgttttttg tgaacatctc tatgggacag
4051 gattctaaca ctgtctctgt catgactaat tttgagtatt ttggtgagtt
4101 tccaactcgc tcacagaaat cttcatagaa tgaatccgga aagagtgact
4151 cttcaaaatc ttcaactaaa tgataagaaa cctctgagag tatgagattt
4201 ctatctctgt gattggccac taaatctctc aaagcttcag aaacacttat
4251 accctcagtg tcttgaacct tttttgggtt ttgtttgtgt tgatactttg
4301 agaaaatctt gtctatagaa catctgatct tactcagaga ttcagatggc
4351 aagagttctt caagtggtac tgaatcttcg ctctcctcga gatctattga
4401 ttctgacaca ctagtctgac tatcccttgt tgttgttttt ttcttctttt
4451 cttttctatt ttcttcagcc attgtgtgtg aaattgattt caggattttg
4501 tattccagtt gttcaggact taagcaaaac ttagttttat tgtggaactt
4551 ctcaacaata tcacacaggg aaactccgac caacttatca taatcatagt
4601 ccacagaatt ccccttatca tcagtctttg ggattacaac actcttattg
4651 ctagacagat caagtgcagt cgaacaacgt gcatctttca atgggtttgt
4701 tttaatctta gcaagctcat caggggtgaa gccactggtt gaattaacga
4751 aagataacat cagcgatagc atctgttttg aaacaccagg tgccttgaca
4801 tcaaattcat ctttgttcag aaaccttgag ccactctcta gtaacagtga
4851 cgactcttct ttcgtaacgt cgttcttggg gttgacaaaa acgcttttaa
4901 atttcaactt tggttccaag aatttttcaa agcattttat ctgatctgtt
4951 accctgtccg gcgtctcttt agttatgaaa tggcaaatgt aggacaggtt
5001 gagaagaaat ttgaaccgac tagtgagcat agtttcaaca ctgtcaccca
5051 atacaagaat catcactttt cttacacatc tatagattag atactcactc
5101 tttgtgatta aatcttcctt caccttttcc atcaaatcaa catgatgtgc
5151 aaggccaaag aaagccatga tgaagtatct aaggttttgt aagaactttt
5201 ggctcctttt gctaggattc aaaagtactg acatgaaaat tatcttcaat
5251 agaattttaa tttcatcaat gcagccttcc agctccttta catcagaaag
5301 ccactgcacc attgtatcga tgacaccctt gatcacctcc gaggacatta
5351 ttggcaaaaa gtatctcttg gggtcagcat aaaaagaaca gatgtgctca
5401 ccatccctat ttatagaata gcattttgaa gactcaccag ttttctggta
5451 aatgagagta aatgtacctt tgggagactt tatttcttgg aaaaaacact
5501 cttcacaact cactcttcca tatctgttct ttccactagc attttgtctt
5551 atcttagata ctgatgatgt cttcattgag tttaccaaac tcaaagataa
5601 cgaagaaatc atgcggaggt cagttatgtc ctcactaaaa ctggtttcat
5651 ccaagtgcat ttggggtctg aagttatctc tctcataatt cataactggg
5701 atgcttcctg actttttaaa agacataaaa tcttcaagag acggccaatt
5751 ctcgaaatca gaggcctcaa gtccataact gtgagcggta agcccatgag
5801 catttagact attgaagact ttgttaagaa tcaaccttct atagtctaga
5851 aagatttcat taagcgcttt ggtcttaccc ttacttttgt tttttggcat
5901 tctactaagt ctgaataaat gctttttaag atctctctga gttgacatca
5951 ctgacacaag tctatctgag actgtggtga atgactgccc gcaccagaca
6001 gactcatcat catcccctct aggaaactca ttctttaatg aaattagatg
6051 acttaaccta acaacatcaa gacctaggag cagtttcctt cttgtgttca
6101 ttagtttgat actctttgat ttattcaaca tgctaatcat tccacatgat
6151 tttctatgat aatgacggtc gttcccaacc ttttcggcct tatcctgttc
6201 ggggtgtcct tcatcattct tagagtcaaa ataaatgaaa ttggtgaatg
6251 atgttgcttc tttgaaatct cgcagcaact cccacttgga ttctggtgct
6301 gatgaaactc cctgatctaa gtacaagtca cagaattctt tcagcaacct
6351 ttctttgtct gtcatcatga ataagggtgg gatgactccc ttcttcaact
6401 tcgctttgaa ttctaagaag ttctccacta tcttggaatt aacctctgac
6451 aagggaatgt ctgggcgcac accttcaaca cacagcctca ttatattctc
6501 gaaatgctca cctgaattat tcttaagcag attgaatgcg tctaaatcaa
6551 agagcttgct accattgcct ttgagtgatt ctgacagcct aatatactct
6601 gactcttcca acatcgcctc attctcttgc acatactcta atagtctgaa
6651 gattaaattc ttaaatttga acaccaccca atcaggaatg gagttgtttt
6701 catacccact cctgcccacc accagtggca caagagtgat ccctgagtgt
6751 tcaagatcac ccctcagtga tgatagcttc ttcatgtcat tgttgtattt
6801 ctgctcatac tctaggggat tcagtctcac aaaacattct agtagaatca
6851 acatgtttcc tgacaccttg aatccgtctg gagtgacaca tggaagagaa
6901 gggacaacaa atccattttc tcttaagata agttccactg acttctcttc
6951 agtgttgtgg atgcaaccat tctcatcgca gatgtcaatc tcaatacacg
7001 tggataatag cttgagaccc tcaatcataa tgaacttggg ctctgtttgg
7051 caaaggactt ttagcttttg gggagctagt ctctcatcat taggaaagtt
7101 tcttgagata agctgcagga gttcattctt taatgagtcc attgtgaatt
7151 ttgtcccata aaa