Sequence of DPV Lactate dehydrogenase-elevating virus
Lactate dehydrogenase-elevating virus polyprotein (ORF1a ORF1b), complete cds, structural glycoprotein (ORF2, ORF3, ORF4, ORF5), complete cds, non-glycosylated envelope protein (ORF6), complete cds, capsid protein (ORF7), complete cds.
ACC No: L13298
Dated: 2000-03-04 | Length: 14225 | CRC: -296265489
!!NA_SEQUENCE 1.0
ID LDVGLYPOL standard; RNA; VRL; 14225 BP.
XX
AC L13298;
XX
SV L13298.1
XX
DT 06-APR-1993 (Rel. 35, Created)
DT 04-MAR-2000 (Rel. 63, Last updated, Version 4)
XX
DE Lactate dehydrogenase-elevating virus polyprotein (ORF1a ORF1b), complete
DE cds, structural glycoprotein (ORF2, ORF3, ORF4, ORF5), complete cds,
DE non-glycosylated envelope protein (ORF6), complete cds, capsid protein
DE (ORF7), complete cds.
XX
KW capsid protein; cysteine protease; envelope protein; helicase; polymerase;
KW polyprotein; serine protease; structural glycoprotein.
XX
OS Lactate dehydrogenase-elevating virus
OC Viruses; ssRNA positive-strand viruses, no DNA stage; Nidovirales;
OC Arteriviridae; Arterivirus.
XX
RN [1]
RP 1-14225
RX MEDLINE; 93276546.
RA Godeny E.K., Chen L., Kumar S.N., Methven S.L., Koonin E.V., Brinton M.A.;
RT "Complete genomic sequence and phylogenetic analysis of the lactate
RT dehydrogenase-elevating virus (LDV)";
RL Virology 194(2):585-596(1993).
XX
DR SPTREMBL; Q06498; Q06498.
DR SPTREMBL; Q06499; Q06499.
DR SPTREMBL; Q06500; Q06500.
DR SPTREMBL; Q06501; Q06501.
DR SPTREMBL; Q06502; Q06502.
DR SPTREMBL; Q06503; Q06503.
DR SWISS-PROT; P24122; NCAP_LDV.
DR SWISS-PROT; P24123; VPX_LDV.
XX
CC On Aug 9, 1995 this sequence version replaced gi:293036.
XX
FH Key Location/Qualifiers
FH
FT source 1. .14225
FT /db_xref="taxon:11048"
FT /organism="Lactate dehydrogenase-elevating virus"
FT /strain="neuro-virulent type C"
FT 5'UTR 1. .161
FT /evidence=EXPERIMENTAL
FT /partial
FT /function="5' untranslated region"
FT CDS 162. .6842
FT /codon_start=1
FT /db_xref="SPTREMBL:Q06502"
FT /note="ORF1a; putative"
FT /function="cysteine protease/serine protease/unknown"
FT /product="polyprotein"
FT /protein_id="AAA74103.1"
FT /translation="MQSGFDRCLCTPNARVFWERGQVYCTRCLAARPLLPLSQQHPRLG
FT ALGLFYRPASPLSWEAPVTYPTKECRPGGMCWLSSIYPIARMTSGNHNFQARLNFIASV
FT VYRDGKLTSKHLEEDFEVYSRGCRWYPITGPVPGIALYANAVHVSDESFPGATHVLSNL
FT PLPQQPLRKGLCPFADARANVWRYKGNTVFVSPQGYLWTTGSNDSVPEPWGEDRRLCEK
FT IISSLPADHLVKINFSNYPFDYSFTGGDGAGFVVFPCKERDTKFSKCWEKIFEDHSGWM
FT AACEEADLADRMGYRTPAGVAGPYLARRLQVRGLRAVVKPENNDYIVWALGVPESYIRH
FT VSRAGEPVEEFFVKVGEFSIVSNCVVTPHPKFRFQTRKYYGYSPPGDGACGLHCISAML
FT NDIFGDSFTTRLGKCSRDSSEWLSDQDLYQLVMTANLPATIGHCPSAIYKLDCVNQHWT
FT VTKRKGDRAVGRLAPDCLRGVCGECEMGIHIGADTDLSPIVELQLAQDVSPRPGALLWF
FT LELHELCVVDDDFAHAIARAGEEYRRAMGIPRDDWVILAELMTENCRTRHQVLEKLQRG
FT LQLQASSRPSSPASVSPASSVDLSAAGLLLSGTESDKEAVVAVNDGCYTVLGFDKNEAT
FT KSEQDLATDLFCDLVKPMETSTTKLESRKILEAAAKALESCKPKRKRSRKKKTRTPSPT
FT CSVDAAVAEPTSVNSLGNQDTRETCASEKKAEKCPTPTPPPRPKRAALKNSNSGCVLKD
FT IIWNQTGPGVKCLTIVEDVRAFLKGITPPGGVLSTRSRITKHIVDHFHSICEQTPELVL
FT AHAEHQAKNLHELLASETAKLILGIGEDPLKKLVGSQRSLPRRLGFGAWLGGQQKTSGG
FT CGEREFKDVGRKSGAERTPSKRDLGVSLGDQLSQDGARRLSSSTACEIKESVPPIIDSG
FT GGLSQKFMAWLNHQVFVLSSHLLAVWSFIFGSRQVLGVFDYVYTLFCLCCVLLCFYLPA
FT IGFMTLVGCVFGSPWRVRLSVFSVWLCVAVVVFQEVLPEPGAVCTSASAERAAALERYT
FT SNGVHRPVNHLSVGLVGTVAGFVARSVGGPRRYWFYFLRLMVLLDLGLVFLAVALRGSC
FT KKCFCKCVRTASHEVQLRVFPSTKVARTTLEAICDMYSAPRVDPIFIATGVRGCWTGSV
FT SPHQVTEKPVSYSNLDDKKISNKTVVPPPTDPQQAVRCLKVLQCGGSIQDVSVPEVKKV
FT TKVPFKAPFFPNVTIDPECYIVVDPVTYSAAMRGGYGVSHLIVGLGDFAEVNGLRFVSG
FT GQIADFVCLGLYVLLNFLLSAWLSSPVSCGRGTNDPWCRNPFSYPVVGQGVMCNSHLCV
FT AEDGLTSPMTLSYSLIDWALMVAIMATVAIFFAKISLLVDVVCVFCCLLMYAFPSLSIA
FT AFGFPFVLCKVSLHPITLVWVQFFLLAVNVWAGVASVVVLISSWFLARATSSLGLITPY
FT DVHMITATPRGASSLASAPEGTYLAAVRRSALTGRCCMFVPTNFGSVLEGSLRTRGCAK
FT NVVSVFGSASGSGGVFTINGNPVVVTASHLLSDGKARVSCVGFSQCLDFKCAGDYAFAR
FT VANWKGDAPKAELSHRRGRAYCSPLVGLSLDLLGKNSAFCFTKCGDSGSPVVDEDGNLL
FT GIHTGSNKRGSGMVTTHGGKTLGMANVKLSEMCPHYSGPGVPVSTVKLPKHLVVDVETV
FT XSDLVAVVESLPALEGALSSMQLLCVFFFLWRLIHVPDVPVIRIAFFFLNEILPVMLAR
FT LMFSFALSLFFCVHWLFCSSVAVAFGDCCSKSVTGYSVQVLLLRLVIAALNRPCGPFGF
FT SLLGQLSQCCLMLCLLDIELQLLGCLYLGQLLMWPPKEIFFHPTGQFMFLPLFLSLFKR
FT NALADMLVGNGCFDAAFFLKYFAEGNLRDGVSDSCNMTPEGLTAALAITLSDDDLEFLQ
FT RHSEFKCFVSASNMRNGAKEFIESAYARALRAQLAATDKIKASKSILAKLESFAGGVVT
FT QVEPGDVVVVLGKKVIGDLVEVVINDAKHVIRVIETRTMAGTQFSVGTICGDLENACED
FT PSGLVKTSKKQARRQKRTGLGTEVVGTVVIDGVSYNKVWHIATGDVTYEGCLVTENPQL
FT RPLGMTTIGRFQEFIRKHGEKVKTSVEKYPVGKKKSVEFNITTYLLDGEEYDVPDHEPL
FT EWTITIGESDLEAERLTVDQALRHMGHDSLLTAKEKEKLARIIESLNGLQQASALNC"
FT misc_feature 6828. .6915
FT /evidence=EXPERIMENTAL
FT /standard_name="ribosomal frameshift region"
FT /function="frameshift [minus 1] at orf1a/1b junction"
FT CDS <6839. .11074
FT /codon_start=1
FT /db_xref="SPTREMBL:Q06503"
FT /note="ORF 1b; putative"
FT /function="polymerase/zinc-finger/helicase/unknown"
FT /product="polyprotein"
FT /protein_id="AAA74104.1"
FT /translation="LATSGLDRCTRGGLTVXGDAVKLVRYHSRTFSIGDVNLKVMGREE
FT YGRTVGKQGHCLVANLVDGVVVMRKHEPSLVDVLLTGEDADLISPTHGPGNTGVHGFTW
FT DFEAPPTDLELELSEQIITACSIRRGDAPSLDLPYKLHPVRGNPYRDRGVLYNTRFGDI
FT KYLTPQKTKEPLHAAACFNPKGVPVSDSETLVATTLPHGFELYVPTIPQSVLEYLDSRP
FT MHRKCCVRAVVRGLAECDLQKFDLSRQGFVLPGVLYMVRRYLCRLVGIRRRLFLPSTYP
FT AKNSMAGINGNRFPTHVVQSHPDIDALCERACKEHWQTVTPCTLKKQYCSKAKTRTILG
FT TNNFVALGLRSALSGVTQGFMRKGIGSPICLGKNKFTPLPTKVSGRCLEADLASCDRST
FT PAIIRWFTTNLLFELAGPEEWIPSYVLNCCHDAVSTMSGCFDKRGGLSSGDPVTSVSNT
FT VYSLVIYAQHMVLSAFRCGHKVGGLFLRDSLEMEQLFELQPLLVYSDDVVLYDESSELP
FT NYHFFVDHLDLMLGFKTDRSKTVITSDPQFPGCRIAAGRVLVPQRDRILAALAYHMKAS
FT CVSDYFASAAAILMDACACCDYDEDWYFDLVCGIADCARKEGFRFPGPSFYVDMWKRLS
FT VEEKKKCRTCAHCGAPSTLVSSCGLNLCDYHGHGHPHCPVVLPCGHAVGSGVCDGCSSP
FT VMSLNTELDKLLACVPYHPPKVELLSVNDGVSSLPPGRYQARGGVVSVRRDILGNVVDL
FT PDGDYQVMKVAQTCADICMVSINSHILRSQFITGAPGTGKTTYLLSVVRDDDVIYTPTH
FT RTMLDVVKALGTCRFDPPKDTPLEFPVPSRTGPCVRLIRAGFIPGRVSYLDEAAYCNPL
FT DVLKILSKTPLVCVGDLNQLPPVDFIGPCYAFALMLGRQLIEVFRFGPSIVNPIKKFYR
FT EELVSRGPDTGVKFLKSYQPYGQVLTPYHRDRVDGAITIDSSQGCTYDVITVYLPTPKS
FT LNSARALVAITRARFYVFVYDPHNQLEQYLNMSEHEPAGAVAFWCGEQPMMISEGRVQR
FT LSGPAQTTDPKLQQLMGLEGTASPLPQVAHNLGFYYSPDLVQFARIPSELCKHWPVVTA
FT QNRTDWPDRLVCSMSKIDKCSRAIFCAGYHVGPSVFLGVPGVVSYYLTKFLKGKPVPLP
FT DSLMSTGRIALNVREYLDEKEMEFSSRCPHAFIGEVKGSNVGGCHHVTSRYLPPVLVPG
FT SVVKIGVSCPGKAAKELCTVTDVYLPELDPYLNPPTKSMDYKLLVDFQPVKLMVWKDAT
FT AYFHEGIRPMESMSRFLKVPQEEGVFFDLDEFVTNAKVSKLPCKYSVSANQFLTDVVLS
FT MTHPSLAPPDYELLFARAYCVPGLDVGTLNAYIYRRGPSTYTTSNIARLVKDICCPVGC
FT KGSGYMFPK"
FT CDS 11114. .11797
FT /codon_start=1
FT /db_xref="SPTREMBL:Q06498"
FT /note="ORF2; putative"
FT /product="structural glycoprotein"
FT /protein_id="AAA74105.1"
FT /translation="MRLYNLLCPYLTSWFFLVFCLALPSPAGCWFGLSDWFSPRSTVRV
FT EKMTSLTFRSYFRDAIKLCRPDVIHFGKGFGLLWHMKVATMLDDVIHSRLMSHMSHQGR
FT ETWGQIFTHKALENIATPTFCPISSQMAGLEREACTYLLSRLPAIQAASAVYNVTIKFL
FT NQTVLIDFGPSNSSLSVAEHLWLVSMQSSVFSSVSAAVALWIVMLLRLPKRVFGFPFMK
FT RARRI"
FT CDS 11665. .12240
FT /codon_start=1
FT /db_xref="SPTREMBL:Q06499"
FT /note="ORF3; putative"
FT /product="structural glycoprotein"
FT /protein_id="AAA74106.1"
FT /translation="MASFNAIICVFICFSCCCIVDCNVTAPTKTCLWFPIHETGKTHLE
FT LSLNFTLCKMCGVVENSYYSHPFCVTDDTCEESSSQYLDFDFPDDVQLLTSIYGTIAIN
FT ALVFAIHQVPEMFGNVTAIHFSENTLCYNSTPIEHGKNVTTSLAIFDGDVSKWYVLEYI
FT RPLFSSWLVLNVSYFLRRSTAGRATRRL"
FT CDS 12132. .12659
FT /codon_start=1
FT /db_xref="SPTREMBL:Q06500"
FT /note="ORF4; putative"
FT /product="structural glycoprotein"
FT /protein_id="AAA74107.1"
FT /translation="MVCLRIYPTLVFILVGFECFLFSQALHCRPCYTKAVSVLNHSNIP
FT LGNGLLMHTQGCHMKRSRGGDPCYTWIGQGEGVGINFNYTGAGHDHVANLVTLAACLIH
FT AVELKETGFHPQFFNVSGHLAVCVNFTEYVSHVQNKTWHEALKLRPAHFLSPSVVKWGT
FT VITLVLAVLLAL"
FT CDS 12611. .13255
FT /codon_start=1
FT /db_xref="SPTREMBL:Q06501"
FT /note="ORF5; putative"
FT /product="structural glycoprotein"
FT /protein_id="AAA74108.1"
FT /translation="MGDGYNLGFGRFVGIMTCLNRLGGFLIPSWLLPYYFVLYILSTEN
FT ACVAGDSSTKNLIYTSTLCELNVTGFQQHFGYAVETFVIFPAVTHLISLKFLTTAHLLD
FT FLSLGVVAGGGYWHQQYVVSSIYASCALLAFIFFCCRAVRNCMSWRYKCTRFTNFVLDT
FT KGRVFRNRSSVLVEQHGKVLLQGQPIEVKTVVLDGVKAVRAKTVPAEKWEA"
FT CDS 13243. .13758
FT /codon_start=1
FT /db_xref="SWISS-PROT:P24123"
FT /evidence=EXPERIMENTAL
FT /note="ORF6; non-glycosylated envelope protein"
FT /product="envelope protein"
FT /protein_id="AAA74109.1"
FT /translation="MGGLEFCDQTSWYQIFIAFSLTYTPIAIYSLKVFRGTLAGIVNIF
FT IFINCCVSFVYLMYHHSVTNTIALSLGAVIALVWGIYTLVKIVDWLVIRCRLCFLGRSY
FT ILAPPSHVDTSDGRQSLTTSLTTAFVVRKPGSTLVNGQLVPDFQRLVLGGKKAVSKGAV
FT NLLKYVSK"
FT CDS 13745. .14092
FT /codon_start=1
FT /db_xref="SWISS-PROT:P24122"
FT /note="ORF7; putative"
FT /product="capsid protein"
FT /protein_id="AAA74110.1"
FT /translation="MSQNKKKGGQNKGANQQLNQLISALLRNAGQNKGKGQKKKKQPKL
FT HFPMAGPSDLRHVMTPNEVQMCRSSLVTLFNQGGGQCTLVDSGGINFTVSFMLPTHATV
FT RLINASANSSA"
FT 3'UTR 14093. .14172
FT /evidence=EXPERIMENTAL
FT /function="3' untranslated region"
XX
SQ Sequence 14225 BP; 3285 A; 3220 C; 3690 G; 4014 T; 16 other;
L13298 Length: 14225 May 27, 2002 15:30 Type: N Check: 6093 ..
1 nnngctttcc gaaaagattg tgtgaacccg tgcggtaacc gtctatttca
51 aggagccact gggacagtgg cccgcaactt gagggtggta gccaaactcc
101 tactacacct ccttctctaa catttccggg tgagcatcct atccgccatc
151 cacctataac catgcagtcg ggattcgacc ggtgtttgtg tacccccaat
201 gctagagtgt tttgggagcg tgggcaagta tactgcacac ggtgcctggc
251 ggcacggccc ctactcccct tgagccagca acatccccgg ctgggcgccc
301 ttgggttgtt ctacaggcca gcttccccgc tatcgtggga ggcgccagtg
351 acctacccta ccaaggagtg ccggccgggt ggcatgtgct ggctttcgag
401 catctacccg atagctcgaa tgacttctgg taatcacaac tttcaggcta
451 gattgaattt catcgcctcw gttgtgtacc gagatggaaa actgacgagc
501 aaacatcttg aggaagactt tgaggtttat tcacgtggat gccggtggta
551 cccaatcacc ggacccgtac caggtattgc gctgtatgca aatgcggtgc
601 atgtgagtga tgagtcattc cctggtgcca cgcacgtttt gagtaacctc
651 cccttgccac aacaaccgct ccgcaaaggt ytatgtcctt ttgctgatgc
701 acgagcgaat gtgtggcgtt acaaaggtaa tactgtgttt gtttcaccac
751 agggttacct gtggacaaca ggctcaaatg attctgtccc agaaccatgg
801 ggtgaggatc gcaggctgtg tgaaaagatc atttcttcac ttcctgcaga
851 ccacctcgtc aagattaatt tttccaacta cccgtttgat tattccttca
901 ccggcggtga cggagcgggc tttgttgtgt tcccgtgcaa ggagcgcgac
951 acaaagtttt ccaagtgttg ggaaaagatt tttgaagacc atagtggctg
1001 gatggccgcc tgcgaggaag cggatcttgc cgaccggatg ggttaccgga
1051 cccctgctgg agttgccggt ccctatttgg ctcgtagatt acaggtccgc
1101 ggattgcgag ctgttgtcaa gcctgaaaac aatgactaca ttgtgtgggc
1151 actgggtgtg ccggagtcct acataaggca tgtctcacgg gctggtgagc
1201 ctgttgaaga attttttgtg aaggtgggtg aattctccat cgtttcaaac
1251 tgtgtagtca ccccccaccc caaatttaga ttccaaacta gaaaatacta
1301 tgggtactct cccccagggg atggagcttg tggccttcat tgcatttcgg
1351 ctatgctaaa tgacatcttc ggtgattcat tcaccacgag attgggtaag
1401 tgtagccgag acagcagcga gtggctttct gatcaagact tgtatcaact
1451 ggtgatgacg gccaacttgc cagctaccat tggccattgc ccgtctgcta
1501 tttacaaact ggattgtgtg aatcagcact ggactgtgac taaaagaaaa
1551 ggtgacaggg ccgtcggaag actggctcct gactgtcttc gtggcgtgtg
1601 tggcgaatgc gaaatgggta tccacatcgg cgctgacact gatttgtcgc
1651 ccattgtgga gctccaacta gcacaagatg tttcgcctcg gcctggagcc
1701 ttattgtggt tcttggaact tcacgaactc tgtgttgtgg acgacgactt
1751 cgcccacgcg atagctagag caggtgagga gtacaggaga gctatgggta
1801 tccccagaga tgactgggta attctagcag aacttatgac tgaaaattgc
1851 cgaactcggc atcaagtgct ggaaaaactt cagcgaggac ttcagcttca
1901 ggcttcgtcc agacccagtt ctcctgcatc agtgagcccg gctagcagtg
1951 ttgatctcag cgctgctggc ttgttgctga gcggtactga gtctgacaaa
2001 gaagctgttg tagctgtgaa cgatggttgc tacacagtac ttggctttga
2051 caagaacgag gcgaccaagt ctgagcaaga tctagcaacg gacttgtttt
2101 gcgaccttgt gaaacccatg gagacttcca ccaccaaact tgaatcaaga
2151 aagattttgg aggctgctgc aaaagcccta gagagctgca agccaaagcg
2201 caagcgcagc agaaagaaga agacccgtac cccttcccca acatgctcgg
2251 tggatgctgc tgtagcggaa cctaccagtg tgaattcgtt ggggaatcag
2301 gatacaaggg aaacatgtgc ctcagagaaa aaggctgaga agtgccccac
2351 gccaacgccg cccccgcggc caaagcgtgc agcactgaag aattcaaact
2401 cagggtgtgt tctgaaggac atcatctgga accagactgg gcctggtgtg
2451 aagtgtctga ccatcgtcga agatgttagg gcattcctaa agggcatcac
2501 cccaccgggc ggtgtgctga gcactagatc ccggattaca aaacacattg
2551 tggaccactt ccacagcatt tgtgagcaaa ccccagaact tgttcttgct
2601 cacgcagaac accaggcaaa aaatctgcat gagttactcg cgagtgaaac
2651 agcaaaactt atccttggga ttggagagga ccccctcaaa aagctggtgg
2701 gctcgcagcg ctccttaccc aggcgacttg ggtttggcgc ctggttgggc
2751 ggccaacaga agacttctgg cggctgtggc gagagagaat ttaaggacgt
2801 tgggcgaaag agcggcgccg agcgcacacc gtccaagcgg gatctaggag
2851 ttagccttgg cgaccagctt tcacaagacg gggcgcggag gttgagttca
2901 tccactgctt gtgagatcaa ggagagcgta ccacctataa tagattccgg
2951 tggcggtttg agtcaaaagt ttatggcttg gttgaatcac caggtttttg
3001 tcttgtcctc ccatctcctt gccgtgtggt ctttcatctt tggctctcgc
3051 caagtgcttg gtgtttttga ttatgtttac acattgtttt gtttatgctg
3101 tgtgttgttg tgtttttacc ttccagccat cgggttcatg accctcgttg
3151 gttgtgtttt tgggtctcct tggagagttc gcctatctgt tttttctgtt
3201 tggctttgtg ttgcagtggt ggtgttccag gaggtcctgc ctgaacctgg
3251 ggctgtctgt accagtgctt cggctgagcg cgcggcagct cttgagcgct
3301 ataccagtaa tggtgttcac cgacctgtta accatcttag tgttggtctg
3351 gtgggcaccg tggcaggatt tgttgctcgc tcggtggggg gcccacggcg
3401 ttactggttt tatttccttc gccttatggt gttattggac ttgggacttg
3451 tgtttcttgc cgtggctttg cgcgggagtt gcaaaaagtg cttctgcaag
3501 tgtgtgagaa cagcttcaca tgaggttcag ctgcgtgtgt tcccatcaac
3551 taaggttgca agaactacct tggaggcaat ctgtgacatg tacagcgcac
3601 ctcgagttga tcccatcttc atcgcaactg gcgtgagggg ttgttggact
3651 gggagtgtta gccctcatca ggtgacagag aagcctgtca gctacagtaa
3701 cctggatgac aaaaagattt ccaacaaaac agttgtccct cctcctaccg
3751 acccacaaca ggctgtcaga tgcttgaagg tgctccagtg cggagggtcc
3801 atccaggatg tttccgtgcc tgaggttaag aaggttacaa aagtcccatt
3851 caaggccccc tttttcccca atgtcacaat tgatcctgag tgctacatcg
3901 tggttgaccc agtcacttac tccgcagcga tgcggggcgg gtatggtgtg
3951 tcacacttga tcgttggatt gggtgatttc gcagaggtca acgggctcag
4001 gtttgttagt gggggccaaa ttgctgattt tgtctgcttg gggctgtatg
4051 ttttgcttaa tttccttctt tcggcctggt tgtccagccc tgtgagttgt
4101 ggacgaggta ccaatgatcc ctggtgcagg aaccctttct cttacccagt
4151 ggtgggtcaa ggggttatgt gcaattcaca tttgtgtgtt gcggaggatg
4201 gtttgacatc accaatgact ttgtcctata gcttgattga ttgggcgctc
4251 atggttgcca tcatggcgac agtggccatt ttctttgcta agatctcatt
4301 gcttgtggat gttgtttgtg tgttttgctg cctattgatg tatgccttcc
4351 ctagtttgtc tattgctgcc tttgggtttc cctttgtttt gtgcaaagtt
4401 tcattgcatc ccataacatt ggtttgggtg cagttctttt tgctggcagt
4451 gaatgtgtgg gcaggtgtgg cctcagtggt agtgttgatt tcctcctggt
4501 ttttggctcg agccacatca tcgctcggct tgattacccc atatgatgtg
4551 cacatgataa cagctacacc acgtggagca agctcattgg cctccgcccc
4601 agaaggtacc tacctggcag cggtacgtcg gtctgcattg actggacggt
4651 gctgcatgtt tgtcccaact aactttggta gtgttcttga gggcagtctc
4701 agaaccaggg gctgtgcaaa gaacgtggtg tctgtcttcg ggtcggcatc
4751 cggctccggg ggcgtcttca caatcaatgg caaccccgtg gtggtaactg
4801 catcccacct gctatctgat ggtaaggcac gagtgtcatg cgttgggttt
4851 tcccagtgcc tggatttcaa gtgtgccggt gattatgcat ttgctagggt
4901 cgctaactgg aagggcgatg ctcccaaggc tgaattgtca catcggagag
4951 gccgagctta ttgctcaccg ctagtggggt tgagcctgga tttgttgggg
5001 aaaaattctg ccttctgctt cacaaagtgt ggggactcag gttcacctgt
5051 tgttgatgag gatggcaact tgctaggaat ccacaccggc tccaacaagc
5101 gtggatccgg gatggttaca acacatggtg gcaagactct gggaatggca
5151 aatgttaagy tgagtgagat gtgtcctcat tacagtggcc cyggtgtmcc
5201 ggtgtcgaca gttaaattgc ctaaacatct ggttgttgac gtcgaaaccg
5251 tgyccagtga cttggtagcg gttgtagaat cgttgcctgc acttgaggga
5301 gcactgtcat ccatgcagct gctttgtgtg ttcttctttt tgtggcgcct
5351 gattcatgtc cccgatgtgc ctgtgattcg gatagcattc ttcttcttga
5401 atgagattct gccagtgatg ctagcaaggt tgatgttctc ttttgcattg
5451 tccctgtttt tctgtgttca ctggctattc tgttcaagtg ttgctgttgc
5501 gtttggtgat tgctgctcta aatcggtcac tggatattct gttcaagtgt
5551 tgctgttgcg tttggtgatt gctgctctaa atcggccttg tggtcctttt
5601 ggtttttctc tgttggggca attgtctcaa tgctgtctga tgctgtgtct
5651 cttggatata gaattacaat tacttggctg tttgtaccta gggcagctac
5701 tgatgtggcc ccccaaagaa attttcttcc atcctactgg ccaattcatg
5751 tttttgcccc tatttttgag tttgtttaag cgtaatgcct tggcagacat
5801 gctggtgggg aatgggtgct ttgatgctgc atttttcctg aagtactttg
5851 cggaggggaa tttgcgcgay ggcgtctcag actcctgcaa catgaccccg
5901 gaggggctta ctgccgcgtt ggctattacc ttatctgatg atgacttgga
5951 gtttctgcaa cgtcattctg aatttaagtg ctttgttagt gcttcaaaca
6001 tgaggaacgg cgcaaaggaa ttcattgaat ctgcctatgc ccgagctctc
6051 agggctcaac tagctgccac agataaaatc aaggcctcca agagcatcct
6101 ggccaaactg gaaagcttcg ccgggggcgt ggttacccaa gttgagccag
6151 gagatgttgt ggtagtgctt ggaaagaaag tgatcgggga cctggttgag
6201 gttgtcatca acgatgcaaa acacgtaatt cgtgtgattg aaaccaggac
6251 catggccgga acacaatttt ctgttggcac catctgtgga gatctggaaa
6301 atgcttgtga agaccccagc ggactggtca agacctcaaa gaagcaggcc
6351 cgccgccaga agaggaccgg actgggaact gaggtggttg gtactgttgt
6401 gatcgacggg gtatcttata ataaagtttg gcacatagcc acaggagatg
6451 tgacttacga aggttgtcta gtgactgaga acccccagtt acgcccattg
6501 ggtatgacca caattggtcg cttccaagaa ttcataagga agcacggtga
6551 aaaagtgaag acctcggttg agaaataccc ggtggggaag aagaagtccg
6601 tcgagttyaa cataacaacc tacctgcttg atggtgaaga atatgatgtg
6651 cctgatcatg agccattgga atggactatc accattggag agtctgattt
6701 ggaggcagaa agacttactg tggaccaggc ccttcgtcac atgggccatg
6751 attccttgct gactgcaaag gaaaaggaga agcttgcccg catcattgaa
6801 agtctcaatg gattgcagca ggcatcggct ttaaactgct agccacctct
6851 ggtctcgacc gctgtactag aggtgggctg acggtgtytg gcgatgcggt
6901 caagctggtg aggtatcact cccgaacttt ttccattgga gatgtcaact
6951 taaargtcat gggccgagaa gagtacggcc gtacggtcgg aaaacaaggc
7001 cattgcttag ttgcyaacct ggttgatggc gtggttgtca tgcgcaaaca
7051 cgagccgtcc ctggtagatg tcttattgac tggagaggat gctgatctca
7101 tctcacccac ccacggccct gggaacactg gggttcatgg gtttacctgg
7151 gattttgaag ctcccccaac tgatttggaa cttgaattgt ctgaacaaat
7201 tataactgca tgctccattc gtcgaggtga tgctccctcc ctggacctcc
7251 cttacaagct gcacccagtt aggggcaacc cgtataggga ccgtggagtg
7301 ttgtacaaca cccgatttgg ggacataaaa tacttgaccc cacaaaagac
7351 gaaggaacct ttgcatgctg ctgcatgctt caatcctaaa ggagtgccag
7401 ttagtgactc agaaactttg gttgcgacta ccttgcctca tgggtttgag
7451 ttgtacgtac caacaattcc ccagagcgta ctggaatatc ttgacagtcg
7501 cccgatgcat cgaaaatgtt gtgtaagagc cgttgtgcgt ggtctcgctg
7551 aatgtgacct ccaaaaattt gacttgtcac gacagggttt tgtcttgcct
7601 ggtgtgcttt acatggttcg caggtatttg tgtcgactgg ttggaataag
7651 gcgacgcctc ttcttgccgt ccacttatcc tgcgaagaat tccatggctg
7701 gcataaatgg caatagattt ccaacccatg ttgttcagtc tcacccagat
7751 attgatgcct tatgcgagcg agcttgcaaa gagcattggc aaactgtcac
7801 cccatgtacc ttaaagaaac agtactgttc aaaagctaaa acccgaacta
7851 ttctgggaac caacaatttc gtcgcattgg gccttagatc cgctctgagc
7901 ggggtcacac agggctttat gcgaaaagga attgggtctc ccatttgctt
7951 gggtaaaaac aagttcaccc cgctaccaac caaggttagc ggccgctgcc
8001 tcgaggctga tctcgcctca tgtgaccggt caactccggc aataatcagg
8051 tggtttacca cgaacttgct gtttgagttg gcagggccgg aagaatggat
8101 tccatcttat gttttgaatt gttgccacga tgccgtgagc acgatgagtg
8151 gctgctttga taagaggggt ggattgtcat ctggagatcc tgtgactagt
8201 gtgagcaata ctgtgtatag cttagtcatc tatgctcaac acatggtgct
8251 gtctgcattt aggtgtggtc ataaagtggg aggcttgttc ttacgagatt
8301 cccttgaaat ggaacagctc ttcgaactgc aaccgttgtt ggtgtactcc
8351 gacgatgttg tgctctacga cgaaagtagt gagctgccaa attatcactt
8401 ttttgttgac caccttgatc taatgctggg attcaagact gataggtcca
8451 agactgtcat cacctcagat ccccaatttc ctggctgtcg cattgctgct
8501 ggaagggttt tggtgccaca aagagatcgt atcttagccg cactggcgta
8551 ccatatgaag gctagttgtg ttagtgatta cttcgctagt gctgcggcca
8601 ttctaatgga tgcatgtgcg tgctgtgatt atgatgagga ctggtacttt
8651 gaccttgtct gcggtattgc tgattgtgcc agaaaagaag gattcaggtt
8701 ccctgggcct agcttttatg ttgacatgtg gaaacgcttg tcagttgagg
8751 aaaagaagaa atgcaggacc tgcgctcatt gtggtgcacc ctccactttg
8801 gtgagcagtt gcggcctcaa cttgtgtgac tatcacggtc atggccaccc
8851 tcattgcccg gttgtgctgc catgcggaca cgccgtaggc tcaggtgtct
8901 gtgacgggtg ttcttccccg gtcatgagtt tgaacacaga attggataag
8951 cttcttgcat gtgtcccgta ccacccccca aargtagagt tgctctccgt
9001 caatgacggg gttagtagcc tgccacctgg gaggtatcag gcacgcggag
9051 gagtagtgtc cgtcagaaga gacatccttg gaaatgtggt ggaccttccc
9101 gatggggatt accaggttat gaaggttgca cagacctgtg cagacatctg
9151 catggtttcc atcaacagcc acattctaag atcacaattc atcaccggcg
9201 ccccagggac cggaaagact acttacctac taagtgttgt gagggatgat
9251 gatgtcatat acactcccac tcatagaacc atgttagatg tggtcaaagc
9301 attgggtacc tgtaggtttg atccacccaa ggatacacca cttgagttcc
9351 cggttcctag tcggactggg ccatgcgtcc ggttgattag ggctgggttc
9401 attccgggaa gggtcagtta ccttgatgag gctgcctatt gcaacccatt
9451 ggatgtgctc aaaattctgt caaagacccc cctggtgtgt gttggcgact
9501 taaatcagct tccccctgtc gatttcatcg gaccttgcta tgcattcgcg
9551 ttgatgctag gcagacaact gatagaggtg tttcgattcg ggccctctat
9601 tgtcaaccca ataaagaagt tctacaggga agagttggtt tcacgagggc
9651 ctgatactgg agtaaaattt ctgaagagtt atcaacccta tggacaggtc
9701 ttaacacctt atcatcgtga tcgcgttgat ggcgccatca ccattgattc
9751 tagccagggt tgyacttatg atgtgataac agtgtatttg ccaacaccca
9801 aatcactgaa ttcagccaga gcccttgttg ccataactag agccagattt
9851 tatgtgtttg tatatgatcc tcataatcaa ttagaacagt acttgaatat
9901 gtctgagcat gaaccggctg gcgctgtggc attttggtgt ggggaacagc
9951 caatgatgat ttctgagggg cgtgttcaaa ggcttagtgg accagcacaa
10001 acgactgatc ccaaattgca gcagttaatg gggcttgaag gaactgcgtc
10051 cccactgcct caagttgctc acaacttggg cttttattat tctcctgatt
10101 tggttcaatt tgctaggata ccatcagaat tgtgtaaaca ttggcctgta
10151 gttacggcac aaaacagaac tgactggcct gataggctag tgtgcagcat
10201 gagcaaaatt gacaagtgct ctcgagccat cttttgtgcc gggtatcatg
10251 tgggccccag tgtcttctta ggagtccctg gtgtggtgtc ctattatttg
10301 accaaattct tgaagggaaa gccagttcca ctgcctgatt ccctaatgtc
10351 aacagggaga atagcactga acgtgcgtga atatttggat gaaaaggaga
10401 tggagttttc ctcgaggtgt ccccatgcct tcattggaga agtgaaggga
10451 agtaatgttg gtggatgtca tcatgtaacc tcgagatatc tccctccagt
10501 tctggtcccc ggctccgtgg tgaagattgg agtcagctgt cctggtaaag
10551 cagcaaagga gttgtgcact gtgactgatg tctacctacc ggagctggat
10601 ccttacctta accccccaac aaaaagtatg gactataagc tattggttga
10651 ttttcagccc gtcaagctta tggtttggaa ggatgctaca gcgtattttc
10701 atgaaggcat tcgccccatg gaatccatgt cccggtttct aaaggttcct
10751 caggaggagg gtgtgttctt tgatctggac gaatttgtta caaatgctaa
10801 agtttcaaaa ttaccctgca agtactcggt gagtgcgaat cagtttttaa
10851 ctgatgtcgt gttgtccatg actcacccaa gtctagcccc ccctgattat
10901 gaattgttgt ttgctagagc ctattgtgtg ccggggcttg atgtcggcac
10951 actaaatgca tacatttata ggcgtgggcc atccacctat accacaagta
11001 acattgcccg cttggttaag gacatctgct gtcccgttgg ctgcaaagga
11051 agcgggtaca tgtttccaaa gtgatgggca acattgcaac acttgttaat
11101 aaagccatag aagatgcgtt tgtacaactt gttgtgtcca tacttgacat
11151 cctggttttt cttggtattc tgtttggcct taccatcgcc ggctggctgt
11201 tggtttgggt tatcagactg gttttcgccg cgatctaccg tgcgagtcga
11251 aaaaatgacc agcctgacat tcagaagcta ctttagggat gcaattaagt
11301 tgtgcagacc ggatgtcatc cattttggca aaggttttgg actgctgtgg
11351 cacatgaagg ttgccactat gttggatgat gtaattcata gccgcctaat
11401 gtctcacatg tcccatcaag gtcgtgagac ttggggacaa attttcaccc
11451 acaaggcttt ggaaaacatt gccacaccca cgttctgtcc catctccagt
11501 caaatggcag gtctagaaag ggaagcttgt acctacttgt tgagtagatt
11551 accagcaatt caagctgcat ccgcagttta taatgtaacc atcaagtttt
11601 taaatcaaac agtgctgatt gatttcggcc cgtcaaattc ttccctttca
11651 gttgctgaac atctatggct agtttcaatg caatcatctg tgttttcatc
11701 tgtttcagct gctgttgcat tgtggattgt aatgttactg cgcctaccaa
11751 aacgtgtctt tggtttccca ttcatgaaac gggcaagacg catttagagc
11801 tatccctgaa ttttacattg tgtaagatgt gcggtgtggt tgagaattcc
11851 tattactccc acccgttttg tgttacagat gatacctgcg aagagtcatc
11901 gtcgcagtat cttgattttg attttcctga tgatgtccag ttgttaacat
11951 ctatttatgg taccatagct attaatgccc tggtgtttgc catccatcag
12001 gtccctgaaa tgtttggcaa cgttactgcc atccacttca gtgaaaatac
12051 tttgtgctac aatagcaccc caatagagca tggaaagaat gtaaccacat
12101 cattggctat ttttgatggt gatgtgtcaa aatggtatgt cttagaatat
12151 atccgaccct tgttttcatc ttggttggtt ttgaatgttt cttattttct
12201 caggcgctcc actgccggcc gtgctacacg aaggctgtga gtgtcctcaa
12251 tcattccaac ataccattag gcaatggcct acttatgcac acccaaggat
12301 gccacatgaa aagaagcaga ggtggtgacc catgctatac ttggattggt
12351 cagggcgaag gtgtgggcat taattttaat tatactggtg ccggccatga
12401 tcacgtggcc aatttagtaa ctctagctgc atgcttgatt catgcagtcg
12451 aattgaaaga aactggattt catcctcaat tttttaatgt ttccggccat
12501 ttggccgtgt gtgtgaattt tactgagtat gtgagtcacg tacaaaacaa
12551 aacttggcat gaagctttga agcttcgtcc cgcccatttt ctttcccctt
12601 cagttgtgaa atgggggacg gttataacct tggttttggc cgttttgttg
12651 gcattatgac atgtttaaac agattgggcg ggtttttgat accatcctgg
12701 ctattgccat actattttgt cttgtatatt ctctctaccg aaaatgcctg
12751 cgtcgcaggc gacagctcaa ccaagaactt gatctacacc tcaaccttgt
12801 gtgagctgaa tgtgaccggt tttcaacaac atttcggtta cgcggtagag
12851 acgtttgtaa tttttccagc agtgactcat ttgatttcct tgaagttcct
12901 tacgaccgcc catttgttgg attttctttc attgggcgtc gttgctggag
12951 gaggttactg gcatcagcaa tatgtcgtaa gctccattta tgcaagttgt
13001 gcccttctcg ccttcatttt cttctgctgt cgagcagtta ggaattgtat
13051 gagctggaga tataagtgca ccaggtttac caattttgta ttggatacca
13101 aaggaagagt ttttcggaac cgcagttccg tccttgttga gcagcacgga
13151 aaagtattgc tgcaaggcca acccattgag gtgaagacag ttgtgctcga
13201 cggtgtcaaa gctgtccggg ctaaaaccgt tccagccgaa aaatgggagg
13251 cctagaattt tgtgatcaaa cttcctggta tcagattttc attgccttta
13301 gtttgactta taccccaatt gccatctata gcttaaaagt ttttcgtggc
13351 actttggcag gtattgtaaa tatttttatt tttattaatt gttgtgtaag
13401 ttttgtgtat ttgatgtacc atcattctgt caccaacaca attgctttgt
13451 cattgggtgc tgtgattgct cttgtgtggg gcatttacac ccttgtgaag
13501 atagttgatt ggttggtgat caggtgccgg ttgtgcttcc taggtagaag
13551 ttacatccta gccccaccca gccacgtgga cacctctgac gggcgtcaga
13601 gcctaaccac atcgttaaca accgcctttg tggttaggaa gccaggtagt
13651 acccttgtaa acgggcagtt ggtcccggac tttcaaagac tcgtgcttgg
13701 gggcaagaag gccgtgtcaa aaggtgcggt taaccttttg aaatatgtct
13751 caaaataaga agaagggcgg ccagaataaa ggggcaaacc agcaacttaa
13801 tcagctgatt agtgcgttgc ttcgcaatgc cggacaaaat aaaggaaagg
13851 ggcaaaagaa aaagaagcag cccaagctgc atttccccat ggcaggtcca
13901 tctgacctgc ggcatgttat gactcccaac gaggttcaga tgtgtcgatc
13951 ttcattggtg acccttttta atcagggcgg aggtcagtgc acattggttg
14001 actctggtgg aataaatttc accgtgagtt tcatgttgcc aacgcatgcc
14051 acagtccggt taattaatgc ttctgctaat tcatctgctt aggagttaca
14101 atgtaagtca tgtcagtcag atgcagcgac tcagcctttt gtaattaatt
14151 gcgatttggc tgggccggaa ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa
14201 aaaaaaaaaa aaaaaaaaaa aaaaa