Sequence of DPV Lactate dehydrogenase-elevating virus
Lactate dehydrogenase-elevating virus Plagemann strain, complete genome.
ACC No: U15146
Dated: 2005-04-17 | Length: 14104 | CRC: 738656576
ID U15146; SV 1; linear; genomic RNA; STD; VRL; 14104 BP.
XX
AC U15146;
XX
DT 08-NOV-1994 (Rel. 41, Created)
DT 17-APR-2005 (Rel. 83, Last updated, Version 4)
XX
DE Lactate dehydrogenase-elevating virus Plagemann strain, complete genome.
XX
KW .
XX
OS Lactate dehydrogenase-elevating virus
OC Viruses; ssRNA positive-strand viruses, no DNA stage; Nidovirales;
OC Arteriviridae; Arterivirus.
XX
RN [1]
RP 1-14104
RX PUBMED; 7778295.
RA Palmer G.A., Kuo L., Chen Z., Faaberg K.S., Plagemann P.G.;
RT "Sequence of the genome of lactate dehydrogenase-elevating virus:
RT heterogenicity between strains P and C";
RL Virology 209(2):637-642(1995).
XX
RN [2]
RP 1-14104
RX PUBMED; 7571421.
RA Faaberg K.S., Plagemann P.G.;
RT "The envelope proteins of lactate dehydrogenase-elevating virus and their
RT membrane topography";
RL Virology 212(2):512-525(1995).
XX
RN [3]
RP 1-14104
RA Palmer G.A.;
RT ;
RL Submitted (27-SEP-1994) to the EMBL/GenBank/DDBJ databases.
RL Gene A. Palmer, Microbiology, University of Minnesota, 420 Delaware St.,
RL S.E. Minneapolis, MN 55455, USA
XX
FH Key Location/Qualifiers
FH
FT source 1. .14104
FT /organism="Lactate dehydrogenase-elevating virus"
FT /strain="Plagemann"
FT /mol_type="genomic RNA"
FT /db_xref="taxon:11048"
FT 5'UTR <1. .156
FT /experiment="experimental evidence, no additional details
FT recorded"
FT CDS 157. .6777
FT /codon_start=1
FT /product="polyprotein 1a"
FT /note="ORF 1a; includes two papain-like cysteine proteases
FT and serine protease"
FT /db_xref="GOA:Q83017"
FT /db_xref="UniProtKB/Swiss-Prot:Q83017"
FT /protein_id="AAA85663.1"
FT /translation="MQSGFDRCLCTPNARVFWEHGQVYCTRCLAARPLLPLSQQNPRLG
FT ALGLFYRPATPLTWEAPITYPTKECRPGGLCWLSGIYPIARMTSGNHNFQARLNFVASV
FT VYRDGKLTSKHLEEEFEVYSRGCRWYPITGPVPGIALYANAVHVSDEPFPGCTHVLSNL
FT PLPQQPLRKGLCPFSDARAEVWRYKGNTIFVSEQGYLWTTGSNDSVPEPWGEARRLCEK
FT IIASLPADHLVKIEFSNYPFDYSFTGGDGAGYVLFPCKKNDTKFSKCWEKVFEDHSSWK
FT VACEEADLADRMGYRTPAGVAGPYLARRLQYRGLRAVVKPEQNDYVVWALGVPESYIRH
FT ISRAGEPVENFFVRVGEFSIVSNCVATPYPKFRFQTRKYYGYSPPGDGACGLHCISAII
FT NDIFGDALCTKLTNCSRDSSEWLSDQDMYQLVMTARLPATLGHCPSATYKLDCVNQHWT
FT VTKRKGDRALGGLSPECVRGVCGGECKFVPTYPREINLELAAKSPISALAFSLGVEPYC
FT DCWNFTNSVLVNDSLAVETARAGEAYRSAMGIPKDDWVLLAELMTENCLTRREVLDKLQ
FT RGLRLHATSKPGSPASVSPASSIDFSAAGLLLDGTESDKEAVVAVNNDCYTVLGFDKNS
FT ATKSEQELATGLFSELVEPMETSTSKHESRKILEAASRALKSAKPKRKRNKKKKTSSPT
FT PTPPETPTREVPGAIEVVSGDEEAGACESATIVPDKAQARPPPRPKRQALKKAEQGFIL
FT KDIIWNPTESGVKCLTIVEDVRAFLKSITPPGGALGTRARITAHIVEQFHVIRESTPEL
FT VLAHAEHQAKNMHELLLSEKAKLILGIGEDTLKKLVSSQRSLPRSIGFGAWLSDQQKTA
FT DSCGEREFVEVPLKSGAEPTPSKRDLGVSLGDQLSQDGAPRLSSSTACEIKERVPPIKD
FT SGGGLGQKFMAWLNHQVFLLSSHLLAMWSVVLGSRQKLNWADYVYTLFCLCCVLLCFHF
FT PAIGFIPLAGCVFGSPWRVRLSVFSVWLCVAVVVFQEVLPEPGSVCSSASAECAAALER
FT YSGNGVHRPVNHIGVGLVGTVAGFVARVVGGPRHYWFYFLRLMVVLDLGLVFLAVALRG
FT RCKKCFCKCVRVAPHEVHLRVFPLTKVARPTLEAVCDMYSAPRVDPILVATGIKGCWQG
FT KVSPHQVTDKPVSYSNLEEKKISNKTVVPPPTDPQQAVKCLKVLQCGGSIQDVGVPEVK
FT KVSKVPYKAPFFPNVSIDPECYIVVDPVTYSAAMRGGYGVSHLIVGTGDFAEVNGLRFV
FT SGGHVADFVCLGLYVMLNFLISAWLSSPVSCGRGTNDPWCKNPFSYPVVGQGVMCNSHL
FT CISEDGLTSPMVLSYSLIDWALMIAVIATVAIFIAKVSLLVDVICVFLCLLMYVFPPLS
FT VIAFAFPFALCKVHLHPVTLVWVQFFLLAVNFWAGVAVAVILISSWFLARATSSTGLVT
FT PYDVHLVTSTPRGASSLASAPEGTYLAAVRRSALTGRCCMFVPTNFGSVLEGSLRTRGC
FT AKNVVSVFGSASGSGGVFTIHGNPVVVTATHLLSDGKARVSCVGFSQCLTFKSVGDYAF
FT ARVAEWKGDAPKVELSDRRGRAYCSPQVEWSLVLLGPNTAFCFTKCGDSGSPVVDEDGN
FT LIGVHTGSNKRGSGMITTHNGKTLGMSNVKLSEMCQHYGGSGVPVSTVRLPKHLIVDVE
FT AVASDLVAVVESLPTPEGALSSVQLLCVFFFLWRLIHVPFVPVIAVAFFFLNEILPVVL
FT ARLMFSFALSLFSVFTGFSVQVLLLRLVIAALNRSAVSFGSFLLGQLFHCCLMPSHLET
FT LGPVPGYFYPSTTEVASKEIFVTLLAIHVLALLLSLFKRPMLADVLVGNGSFDAAFFLK
FT YFAEGNLRDGVSDSCNMTPEGLTAALAITLSDDDLEFLQRHSEFKCFVSASNMRNGAKE
FT FIESAYARALRAQLAATDKIKASKSILAKLESFAGGVVTKVEPGDVVVVLGKKIVGDLV
FT EITINDVKHVIRVIETRVMAGTQFSVGTICGDLENACEDPSGLVKTSKKQRRRQKRTGL
FT GTEVVGTVEIDGVSYNKVWHKATGDVTYEGFLVSENSRLRTLGTSAIGRFQEFIRKHGS
FT KVKTSVEKYPVGKNKHIEFAVTTYNLDGEEFDVPDHEPLEWTITIGDSDLEAERLTVDQ
FT ALRHMGHDSLLTPKEKEKLARIIESLNGLQQSSALNC"
FT misc_feature 6763. .6850
FT /note="pseudoknot; ribosomal frameshift region; frameshift
FT [minus 1] at orf1a/1b junction"
FT CDS <6774. .11006
FT /codon_start=1
FT /product="polyprotein 1b"
FT /note="ORF 1b; includes polymerase, zinc-finger protein,
FT helicase"
FT /db_xref="GOA:Q83017"
FT /db_xref="UniProtKB/Swiss-Prot:Q83017"
FT /protein_id="AAA85664.1"
FT /translation="LTTSGLERCSRGGVTVSKDAVKIVKYHSRTFSIGDVNLKVMSFDE
FT YRRTMGKPGHLLVAKLTDGVVVMRKHEPSLVDVILTGEDAEFFPRTHGPGNTGIHRFVW
FT DFESPPVDLELELSEQIITACSMRRGDAPALDLPYKLHPVRGDPYRHRGVLFNTRFGDI
FT TYLIPEKTKEPLHAAACYNKGVPVSDSETLVATTLPHGFELYVPTLPPSVLEYLDSRPD
FT TPRMLTKHGCASAAEKDLQKFDLSRQGFVLPGVLYMVRRYLSRLIGVRRRLFMPSTYPA
FT KNSMAGINGGRFPLTWLQSHPDIDALCKRACEEHWQTVTPCTLKKQYCSKSKTRTILGT
FT NNFVALGLRSALSGVTQGFMRKGIGTPICLGKNKFTPLPVRIGGRCLEADLASCDRSTP
FT AIIRWFTTNLLFELAGAEEWIPSYVLNCCHDVVSTMSGCFDKRGGLSSGDPVTSISNTV
FT YSLIIYAQHMVLSAFRCGHKIGGLFLQDSLEMEQLFELQPLLVYSDDVVFYNESDELPN
FT YHFFVDHLDLMLGFKTDRSKTVITSEPKLPGCRISGGRVLVPQRDRIVAALAYQMKASC
FT VGEYFASAAAILMDACACCDHDESWYFDLVCGIAECAGSPWFRFPGPSFFLDMWNRLSA
FT EEKKKCRTCAHCGAPATLVSSCGLNLCDYHGHGHPHCPVVLPCGHAVGSGVCEQCSSSA
FT MNLNTELDILLMCVPYHPPKVELLSVNDKVSSLPPGAYQARGGVVSVRRDILGNVVDLP
FT DGDYQVMKVAQTCADISMVSVNSNILRSQFVTGAPGTGKTTYLLSVVRDDDVIYTPTHR
FT TMLDVVKALKVCRFDPPKDTPLEFPVPGRTGPTVRLIGAGFVPGRVSYLDEAAYCNPLD
FT VLKVLSKTPLVCVGDLNQLPPVGFNGPCFAFSLMPGRQLIEVFRFGPAVVNSIKKFYKE
FT ELVPRGPDTGVKFLKQYQPYGQVLTPYHRDRVDGAITIDSSQGCTYDVVTVYLPTPKSL
FT NSARALVALTRARHYVFIYDPYDQLQQYLQVFEHEPADAWAFWCGDQPKMIVGGVVKQL
FT AGHSRTTDLKLQQLMGLEGTASPLPQVGHNLGFYYSPDLIQFAKIPPELCKHWPVVTAQ
FT NRTEWPDRLVCGMNKMDKNSRAVFCAGYYVGPSIFLGVPGVVSYYLTKYLKGESVPLPD
FT SIMSTGRIRLNVREYLDENEIEFAKKCPQPFIGEVKGSNVGGCHHVTSRFLPPVLVPGS
FT VVKVGVSCPGKAAKGLCTVTDVYLPELDSYLHPPSKSMDYKLLVDFQPVKLMVWKDATA
FT YFHEGIRPMEAMSRFLKVPEGEGVFFDLDEFVTNAKVSKLPCKYSVSAHQFLTEVVLSM
FT TPTSEAPPDYELLFARAYCVPGLDVGTLNAYIYKRGPSTYTTSNFARLVKDTAVPVGCK
FT GSGYMFPK"
FT CDS 11046. .11729
FT /codon_start=1
FT /product="minor structural glycoprotein"
FT /note="ORF 2"
FT /db_xref="InterPro:IPR003434"
FT /db_xref="UniProtKB/TrEMBL:Q83019"
FT /protein_id="AAA85665.1"
FT /translation="MHLFSSLFPSLIFWFSWAFFLGLPSPAGCWFGVSDWFSPRYSVRV
FT ERLTSLTYRRYFRDAIKLCQPDAIHYGKGFGMLWHMKIATMLDDVIHSRLMSHMSHQGR
FT ETWGRVFTQKALENIGRTQVVSHLQQIAGLEREACTYLMSRLPAIQAASAVYNVTIKFS
FT NETIAISFGPSNTSLTVAEHLWLVSMQSSVFSSVAAAFALWIVMLLRLPRSVFGFLSMR
FT RVRRT"
FT CDS 11597. .12172
FT /codon_start=1
FT /note="ORF 3"
FT /db_xref="GOA:Q83020"
FT /db_xref="InterPro:IPR002556"
FT /db_xref="UniProtKB/TrEMBL:Q83020"
FT /protein_id="AAA85666.1"
FT /translation="MAGVNAIFCLFICCSGICFVDCNVTASTQVCLWFPIHETGKTHLE
FT LALNFTLCKMCGVVENSYYSHPFCVTDDTCEESSSQYLDFDFPDDVQLLSSIYGTIAIN
FT ALVFAIHQVPSMFGNVSAVFFSHNSLCYNSTPVEHNQNVTTSLAIFDGDVEKWYVLEYI
FT RPLFSSWLVLNVSYFLRRSTAGRATRRL"
FT CDS 12064. .12591
FT /codon_start=1
FT /note="ORF 4"
FT /db_xref="InterPro:IPR003412"
FT /db_xref="UniProtKB/TrEMBL:Q83021"
FT /protein_id="AAA85667.1"
FT /translation="MVCVRVHSTTLFILVGLECLLLSQALHCRPCYTKAVSVFNHSNIP
FT LGNGLLMHTQGCHITHKKGGDPCYTWIGQGEGVGINFNYTGAGHEHVANLVTLAACLIH
FT AVELKETGFHPQFFNVSGHLAVCINFTEYVSHIQNKTWHEALKLRPAHFLSPSVVKWGT
FT VITLVLAILLAI"
FT CDS 12588. .13187
FT /codon_start=1
FT /product="major structural glycoprotein"
FT /note="ORF 5"
FT /db_xref="GOA:Q83022"
FT /db_xref="InterPro:IPR001332"
FT /db_xref="InterPro:IPR003239"
FT /db_xref="InterPro:IPR003241"
FT /db_xref="UniProtKB/TrEMBL:Q83022"
FT /protein_id="AAA85668.1"
FT /translation="MKCLKKLGSGWIPSRLLPFCFILYFLSTENACAAGNSSTKNLIYN
FT LTLCELNVTGFQQHFGYAVETFVIFPALTHLISLNFLTTAHLLDFLSLGIVAGGGYWHK
FT QYVISSIYASCALLAFIFFCCRAVRNCMSWRYKCTRFTNFVLDTKGKVYRNRSPVLVEQ
FT HGRVMLQGHPIEVKTVVLDGVKAVRAKTVPAEKWEA"
FT CDS 13175. .13690
FT /codon_start=1
FT /product="non-glycosylated envelope protein"
FT /note="ORF 6"
FT /db_xref="GOA:Q83023"
FT /db_xref="InterPro:IPR001332"
FT /db_xref="InterPro:IPR003240"
FT /db_xref="UniProtKB/TrEMBL:Q83023"
FT /protein_id="AAA85669.1"
FT /translation="MGGLEFCDQTSWYQILIAFSLTYTPIAIYSLKVFRGTLAGIVNIF
FT IFINCCVSFVYLMYHHSVTNTVALSLGAVIALVWGIYTLVKIVNWMVLRCRLCFLGRSY
FT ILAPPSHVDTSDGRQSLTTSSTTAFVVRKPGSTLVNGQLVPDFQRLVLGGKKAVSKGAV
FT NLLKYVSK"
FT CDS 13677. .14024
FT /codon_start=1
FT /product="nucleocapsid protein"
FT /note="ORF 7"
FT /db_xref="GOA:Q89680"
FT /db_xref="InterPro:IPR002484"
FT /db_xref="UniProtKB/TrEMBL:Q89680"
FT /protein_id="AAA85670.1"
FT /translation="MSQNKKKSGQNKGANQQLNQLINALLRNAGQNKGKGQKKKKQPKL
FT HFPMAGPSDLRHVMTPNEVQMCRSSLVTLFNQGGGQCTLVDSGGINFTVSFMLPTHATV
FT RLINASANSSA"
FT 3'UTR 14025. .14104
FT /experiment="experimental evidence, no additional details
FT recorded"
XX
SQ Sequence 14104 BP; 3244 A; 3326 C; 3646 G; 3888 T; 0 other;
u15146 Length: 14104 17-APR-2005 Type: N Check: 5039 ..
1 attccgaaaa gattgtgtga acccgtgcgg taaccgtcta tttcaaggag
51 ccactgggac agtggcccgc aacttgagga tagtagccga actcctacta
101 tacctccctc tctaacattt ccgggtgtgc atcctatccg ccatccacct
151 ataaccatgc agtcgggatt cgaccggtgc ttgtgtaccc ccaatgctag
201 agtgttttgg gagcatgggc aagtctattg cacacggtgc ctagctgcac
251 ggccccttct ccccctttcc cagcagaacc ctcggttggg cgccttgggg
301 ttgttttata ggcctgccac accactcacg tgggaggcgc ctattacata
351 ccccaccaag gaatgtcgac cgggtggact atgctggttg tcgggcattt
401 acccaattgc ccgcatgacg tccgggaatc acaactttca ggctcgactc
451 aactttgtcg cctcagttgt gtaccgggac gggaaactga cgagtaaaca
501 tcttgaggaa gaatttgagg tatactcacg cggttgccgg tggtatccta
551 tcactggccc ggtcccaggt attgcactgt atgcaaatgc agtgcatgtg
601 agtgatgaac cattccctgg ttgcacccac gtgttgagca acctcccgtt
651 gcctcagcag cccctccgca aaggtttgtg tccgttctcg gatgctcgtg
701 cggaggtgtg gcgctacaaa ggcaacacaa tttttgtctc cgaacaggga
751 tatttgtgga caacaggttc aaatgattct gttcccgaac catggggaga
801 ggcacggagg ttgtgcgaga agatcatcgc atcactccct gccgaccacc
851 ttgttaaaat tgagttttcg aactacccgt ttgattattc ttttactggt
901 ggtgacggtg caggttacgt cctcttccca tgcaagaaaa atgacaccaa
951 attctcaaag tgttgggaaa aagtgtttga ggaccacagc agttggaagg
1001 tggcctgtga ggaggctgac ctagctgacc gcatgggcta ccgaaccccc
1051 gcaggagtgg ctggccccta tttggcgcgc cgcctgcaat accgcgggtt
1101 gagagctgtg gttaaacctg aacaaaatga ttatgttgtg tgggccctgg
1151 gtgtcccgga gtcttacatc aggcacattt cccgagcggg cgagcctgta
1201 gagaattttt ttgtgcgtgt tggtgagttc tccatcgttt caaactgtgt
1251 ggccaccccc tatccaaagt ttaggttcca aacaaggaag tattacggct
1301 actctccccc aggggacggt gcctgtggac tgcattgtat ttctgctatc
1351 atcaatgaca tctttggtga tgctctttgt accaagctga ctaactgcag
1401 cagggacagc agtgagtggc tgtctgacca agatatgtat caattggtca
1451 tgacggccag actccccgcc acccttggcc actgtccgtc tgctacctac
1501 aaattggatt gtgtaaatca acactggact gtgacaaaaa ggaaaggaga
1551 tcgagccctc ggtgggctct ctcctgaatg tgtacgtggt gtgtgtggcg
1601 gtgaatgcaa attcgtaccg acctacccac gtgaaataaa tttggaactt
1651 gcagcaaaaa gtcccatcag tgccttggcc ttcagccttg gtgttgagcc
1701 ttattgtgac tgctggaact ttaccaactc agtgctagtg aacgatagcc
1751 tcgctgtcga aactgctaga gctggtgagg cgtacagaag tgctatgggg
1801 atccccaagg atgactgggt acttttggca gaactcatga ctgaaaattg
1851 cctgacccgg cgagaggtgc tggacaagtt gcagcgtgga ctcagactcc
1901 atgcgacgtc caagcctggc tcgcctgcct cagtgagtcc agctagcagc
1951 attgacttca gtgctgcagg tctgctcctg gatggcacag aatctgacaa
2001 ggaggctgtc gtggcggtga acaacgactg ctacacagtc cttgggtttg
2051 ataagaactc tgctaccaaa tctgaacaag agcttgctac aggcttgttc
2101 tctgagctcg tggagcccat ggagacttca acgtctaagc atgaatctag
2151 gaaaatcctg gaagctgctt cacgtgcttt gaagagtgca aagcctaagc
2201 gcaagcgcaa taagaaaaag aagaccagct ccccaacacc taccccgcct
2251 gaaaccccaa cccgggaggt ccctggcgcg attgaagttg tgagtggtga
2301 tgaggaagcc ggggcctgtg agtcggctac tatcgtaccc gataaggccc
2351 aagcccgtcc cccgccgcga ccaaaacgtc aggcccttaa aaaggcagag
2401 caggggttca tactaaagga tatcatctgg aatccaactg aatctggggt
2451 taaatgcttg accatcgttg aggatgtgcg ggcatttttg aaaagcataa
2501 ctccccctgg tggggccctg ggcactcgtg ctagaatcac ggctcacatt
2551 gtggagcagt tccacgtgat ccgtgagtca acacctgaat tggttctggc
2601 ccatgctgaa catcaggcca agaacatgca cgagttgctg ctgagtgaaa
2651 aagcaaaact tatccttgga attggagagg acaccctcaa aaagctggtg
2701 agctcccagc gctccttacc caggagcatt gggtttggcg cctggttgag
2751 cgaccagcag aagaccgccg acagctgtgg cgagagagaa tttgtggaag
2801 ttccgctaaa gagcggagcc gagcccacac cgtccaagcg ggatctagga
2851 gttagccttg gcgaccagct ttcacaagac ggggcgccga ggttgagttc
2901 atccactgct tgtgagatca aggagagggt accacctata aaagattccg
2951 gtggcggttt gggtcaaaag tttatggctt ggttgaacca ccaggttttt
3001 ctcttgtcct cccatctcct cgccatgtgg tctgtcgtgc tcggatctcg
3051 ccaaaagctt aattgggctg attatgttta cacattgttt tgcttatgtt
3101 gtgtgttgct atgctttcac ttcccagcca ttggattcat cccccttgcc
3151 ggttgtgttt ttgggtctcc ttggagagtt cgcctatctg ttttttctgt
3201 ttggctttgt gttgcagtgg tggtgttcca ggaggtccta cctgaacctg
3251 ggtctgtctg ttccagtgct tcggctgagt gtgcggcagc tcttgagcgg
3301 tattccggta atggtgttca ccgacctgtt aaccatattg gtgttggtct
3351 ggtgggcacc gtggcaggat ttgttgctcg cgtggtgggc ggcccacggc
3401 attattggtt ttacttcctt cgccttatgg tggttttgga cttgggactc
3451 gtgtttcttg ccgtggctct gcgtggaagg tgcaaaaagt gtttctgcaa
3501 gtgtgtgaga gtggcacccc atgaggtaca tttaagagtt ttccccctga
3551 caaaggtggc tcgaccaaca ctagaggcag tttgtgacat gtatagtgca
3601 ccccgcgttg atcccatcct tgtggctacc ggcatcaaag gctgttggca
3651 gggtaaggtg agccctcacc aggttactga caagccagta agctacagta
3701 acctagaaga aaaaaaaatt tccaacaaga cagtggtccc cccacctact
3751 gacccacagc aagcggtgaa gtgcttaaag gtgcttcagt gcggtggatc
3801 aattcaggat gtcggggtcc ccgaagttaa gaaggtttca aaagtcccat
3851 acaaggcccc attcttccca aacgtctcaa ttgatcctga gtgctacatc
3901 gtggttgacc ctgttaccta ctccgctgcc atgcggggtg gttatggcgt
3951 gtcgcacctg attgtgggca ccggtgattt tgctgaagtt aatgggttga
4001 gatttgtgag cggagggcat gttgcagatt ttgtttgcct gggattgtat
4051 gtaatgctta attttctcat atctgcttgg ctgtctagtc ctgtgagttg
4101 tggacgagga accaacgacc cctggtgcaa gaatccattc tcttatcctg
4151 tggttggcca gggagttatg tgtaactccc acctctgcat ctctgaggat
4201 gggcttacat cccccatggt attgtcatac agcctgattg attgggctct
4251 tatgattgcc gtgattgcaa cagtggccat ctttattgca aaggtttcct
4301 tgttggttga cgtcatatgt gtgttccttt gccttcttat gtacgtcttc
4351 ccccctcttt ctgtaattgc atttgcattc ccatttgcct tgtgtaaggt
4401 gcacctgcac cccgtcactc tggtttgggt gcaatttttc ttgctggcag
4451 tgaatttttg ggctggtgtt gcagttgcgg tgatcctgat ttcatcttgg
4501 tttctggcgc gtgccacatc ctctaccggc ctggttacac cgtatgatgt
4551 gcacctggtg acctccacac cccgcggcgc gagctctttg gcttcggctc
4601 cagaagggac ctacttggcc gcagtccgcc gatcggcgtt gactggccgg
4651 tgctgcatgt ttgtccccac aaactttggc agtgtccttg aagggagcct
4701 taggactaga ggctgtgcta agaatgtggt tagtgtcttc gggtctgcat
4751 ccgggtctgg tggggttttc actattcatg gcaaccctgt ggtagtgact
4801 gctacgcacc tgctgtcaga tggtaaggct agggtttcct gtgtcggctt
4851 ctctcagtgc ttgaccttca agagcgttgg tgattacgca ttcgcccgag
4901 tggctgagtg gaaaggtgac gcgcccaagg tcgagctgtc agataggaga
4951 gggcgagctt attgctcacc gcaagtggag tggagcctgg ttttgttggg
5001 tccaaacact gcgttttgct ttactaagtg tggcgactct ggttccccag
5051 tagttgatga ggatggcaac cttatcggtg tccacactgg ttcaaacaaa
5101 cgcggctcag gaatgatcac aacccacaat ggaaaaaccc tgggcatgag
5151 taatgtgaaa ttgagtgaaa tgtgccagca ctatggcggc tctggcgtgc
5201 ctgtttcaac tgtccgattg cccaagcatc tgatcgtcga cgtggaggcg
5251 gtggctagtg acctggtagc tgtagtagaa tctttgccta cacctgaagg
5301 cgcattgtcc tcggttcagt tgttgtgtgt cttcttcttt ctgtggcgcc
5351 tcattcatgt tccctttgtc ccagtaattg cagttgcatt tttcttcctg
5401 aatgagatct tgcctgtggt gttggccaga ttaatgtttt cttttgccct
5451 atctttgttt tcagtcttca caggcttttc ggtgcaagtg ttgctgttgc
5501 gcctagtaat agcagctttg aatcggtctg ctgtgtcatt cggttctttt
5551 ttgttggggc agttgtttca ttgttgtctg atgccgtctc atttggagac
5601 actaggtcct gtaccaggtt atttttaccc gagcacgacg gaagtcgcct
5651 caaaagaaat atttgttacc ttgcttgcca tccatgtttt ggctttgctc
5701 ctaagcttgt ttaagcgccc catgcttgct gatgtgttag tggggaatgg
5751 cagctttgat gccgcatttt tcctgaagta ctttgctgaa gggaatttgc
5801 gtgacggagt ttctgattcc tgcaacatga cacctgaggg gttgaccgcc
5851 gccctggcga tcaccttgtc tgatgatgac ttggaattcc tacaacggca
5901 ttcagagttc aagtgcttcg tcagcgcttc aaacatgagg aatggagcta
5951 aggaatttat tgagtccgcc tatgctcgtg ctcttagagc tcagctggct
6001 gccacagaca aaattaaggc ctcaaaaagc atcctggcca agctagagag
6051 ctttgctgga ggtgttgtca ccaaagttga accaggtgat gttgtggtgg
6101 tactcggaaa aaagattgtt ggcgacctcg tagagatcac catcaacgat
6151 gtcaaacatg tgatccgagt aattgagaca cgagtaatgg ccggcactca
6201 gttctctgtt ggtaccatct gcggagacct tgagaacgcc tgtgaagatc
6251 ccagtggact cgtcaagacc tcaaagaaac aacgtcgccg ccaaaagcgc
6301 accggactgg gcactgaagt ggtcggcacg gtcgaaattg acggagtaag
6351 ttacaacaag gtctggcata aggctactgg tgatgtgaca tatgaaggct
6401 ttctggtgtc tgaaaactcg agactccgca cccttggcac gtcagcaatt
6451 ggccggtttc aagaattcat cagaaaacat ggcagcaagg taaagacctc
6501 agtggagaaa taccctgttg gaaaaaataa gcatattgag tttgcagtga
6551 ccacctacaa cctggatggt gaagagtttg atgtccccga ccatgagcct
6601 ctggagtgga ccattaccat cggagattct gatctggaag cagaaaggct
6651 cacagtggac caggccctga gacacatggg tcatgactcc ttgctgactc
6701 ctaaggagaa ggaaaagctg gctcgcatca ttgaaagcct caatggtttg
6751 cagcagtcat ctgctttaaa ctgttgacca cctctggcct tgaacgctgc
6801 tctagaggtg gtgtcactgt gtccaaggac gcggtcaaaa ttgtgaagta
6851 tcacagccgg actttctcca ttggtgatgt caacttgaag gtcatgtcct
6901 ttgatgagta ccgtcgtacg atgggaaaac ccgggcattt gcttgtggcc
6951 aaactgactg atggtgtggt tgtcatgcga aagcatgaac cctccctggt
7001 agacgtcatc ttgactggtg aggatgcgga gttcttcccc cgtacccacg
7051 gccccggcaa caccgggatc caccggtttg tgtgggactt tgaatccccg
7101 ccggttgact tagaacttga gttgtcagaa cagattatca cagcatgctc
7151 catgcgcagg ggtgatgccc cagccttgga tcttccttac aaattacatc
7201 ctgtaagagg tgatccttat cgacatcgcg gtgtattgtt caatacccgc
7251 tttggagaca taacatactt aatacctgaa aagacaaaag agccgctgca
7301 tgcggcggct tgttacaaca aaggggttcc tgttagtgat tctgaaactt
7351 tggtggctac gactctaccc cacggttttg agttgtatgt tccgacattg
7401 ccgcctagtg ttttagagta cttggacagt cgccccgata ctccaagaat
7451 gctaacaaaa catggttgcg ctagcgcagc cgaaaaggac ttacaaaaat
7501 ttgacttgtc caggcagggg ttcgtgttgc ctggtgtgct ctacatggtg
7551 cggaggtacc tgagtcggct gattggcgtc agacgtcgcc tgttcatgcc
7601 gtcgacatac cccgctaaga actcgatggc aggcatcaac ggtggcagat
7651 tcccactcac gtggttgcaa tcgcatcccg acattgatgc cctgtgcaaa
7701 cgagcctgtg aggagcactg gcaaaccgtg accccctgca ccttgaaaaa
7751 gcagtactgt tcaaagagca agaccaggac aatactgggg accaataact
7801 ttgttgcact aggcctaagg tccgctctca gcggtgtgac ccagggcttt
7851 atgcgaaagg gcattggaac ccccatctgt ttaggaaaga ataaattcac
7901 cccattgccg gtcaggattg gcggccgttg tctggaggct gacctagcct
7951 catgtgaccg gtcaaccccg gcgattatca ggtggtttac aacaaatctg
8001 ctatttgaat tggctggtgc tgaagaatgg attccttcct acgttttgaa
8051 ttgttgccat gacgtggtca gcaccatgag tggctgcttt gataagcggg
8101 gaggtttgtc atcaggagat cctgttacca gcatcagcaa cacagtttat
8151 agtttaataa tatatgccca acacatggtg ttatcagcat tcaggtgtgg
8201 tcacaaaatt ggaggcttgt ttttgcaaga ctccctagaa atggagcaac
8251 tctttgagtt acaaccgttg ttggtgtatt ccgacgacgt ggttttctac
8301 aacgagagtg atgagttgcc gaactaccat ttctttgttg accacctgga
8351 tttaatgttg gggtttaaaa cagacaggtc caaaactgtc atcacctcag
8401 aacccaaact tcctgggtgc cgcatatctg gcggtagggt cttggtgccg
8451 caacgggatc gtatcgtcgc ggcgctagcg tatcaaatga aggccagctg
8501 cgtcggcgaa tatttcgcta gtgcggcggc tatcttgatg gacgcctgcg
8551 cgtgttgtga tcacgatgag agttggtact ttgaccttgt ctgtggtatt
8601 gctgagtgcg ccggatcccc ctggttcaga tttcccggac ctagcttttt
8651 ccttgacatg tggaaccgcc tttcggcgga agaaaagaaa aaatgtagaa
8701 cctgcgcaca ttgcggggcc ccagccaccc ttgtcagcag ttgtggctta
8751 aacttgtgtg actaccatgg gcatggacat ccacattgcc ctgttgtact
8801 cccatgtggg catgctgtag gatcaggcgt ctgtgaacag tgctcatcct
8851 cagccatgaa tttaaacaca gaacttgaca tactattgat gtgcgtcccg
8901 taccatcccc cgaaagttga gttgctgtcg gtgaacgaca aggtgagcag
8951 cttaccgcct ggggcatacc aggcacgagg tggggttgtg tccgtgagac
9001 gagacatcct tggaaatgtg gttgatctcc cggatggtga ttatcaagta
9051 atgaaggttg cccaaacatg tgctgacatc tcgatggtgt ctgtaaacag
9101 caacatcctc aggtcgcagt ttgtaactgg cgccccgggg actgggaaaa
9151 caacttactt gttgagtgtg gtccgggatg atgatgtaat ctataccccg
9201 acccacagaa ccatgcttga tgtggtcaaa gccttaaaag tgtgcagatt
9251 tgatccacca aaagacaccc cgctggaatt ccccgtccct ggccggaccg
9301 gaccgaccgt tcggttgatt ggcgctgggt ttgttcccgg acgggtgagt
9351 tatctggatg aagcagctta ctgcaaccca ttggatgtgc tcaaagttct
9401 gtcaaaaacc ccattggtct gcgttggtga tttgaatcag ctcccccctg
9451 tgggcttcaa cgggccttgc tttgcatttt ccttgatgcc cgggagacag
9501 ctgattgagg ttttccgttt cggacctgct gtggttaatt ccataaagaa
9551 attttataaa gaagagttgg tgcctcgcgg ccccgacact ggggtcaagt
9601 ttttgaaaca gtaccaaccg tatggacagg tcctgacgcc ttatcatcgc
9651 gatcgcgttg atggagccat caccattgat tccagccaag gctgcaccta
9701 tgatgtggtc acagtgtatc tacccacgcc taaatccttg aattctgcaa
9751 gagctcttgt tgcattgacc cgagccaggc attatgtttt catctatgac
9801 ccatatgatc agttgcagca atatttacaa gtttttgaac atgagccagc
9851 tgatgcgtgg gccttttggt gtggggatca accaaaaatg attgttggtg
9901 gtgttgtgaa acagctggca ggacactcca ggacaactga tttaaaattg
9951 cagcagctga tggggctgga gggcactgct tctcccttgc cccaagttgg
10001 tcataatttg ggtttctatt attcccctga tttgattcag tttgcaaaaa
10051 tacccccaga attgtgtaaa cattggcccg tcgtaacggc ccagaataga
10101 actgagtggc ccgacaggct ggtgtgcggc atgaataaaa tggataaaaa
10151 ttcacgcgct gtcttttgcg cggggtatta tgtaggcccg agtatattct
10201 tgggagtccc tggggtggta tcttattatt tgaccaaata tttaaaaggg
10251 gagagtgtac ccctgcctga ttccatcatg tcaactggga ggattcggct
10301 caatgtgcgc gaatatttgg atgagaatga aattgaattt gcaaagaaat
10351 gccctcagcc cttcattggc gaagtcaagg gaagcaatgt tggtggatgt
10401 catcatgtaa cctctaggtt cctaccccca gttcttgttc ctggctcagt
10451 tgtaaaggtt ggcgtcagtt gtccaggaaa ggccgcaaaa gggctgtgta
10501 ctgtgactga tgtctaccta ccagaattgg attcttacct tcacccccct
10551 tcaaagagca tggattacaa gctactggtt gattttcagc ccgtcaagct
10601 tatggtgtgg aaagatgcta ctgcgtattt tcacgagggc atacgcccca
10651 tggaagccat gtctcgcttc ttaaaagttc ctgaagggga gggcgtcttc
10701 tttgatttgg atgaatttgt caccaatgct aaggtgtcca aattaccttg
10751 caagtactca gtgagtgctc atcagtttct gactgaagtc gtcctgtcaa
10801 tgacgcctac aagtgaagct ccacctgact atgaactgct gtttgcaaga
10851 gcctattgcg tgccggggct tgatgtcggc acgctaaatg catacattta
10901 caaacgtggg ccatccacct ataccacaag taattttgcc cgccttgtaa
10951 aagatactgc agtacccgtt ggctgtaaag gcagtgggta catgtttccc
11001 aagtaatggg taatgttgca actcttataa acaaggctat tgaagatgca
11051 tttattcagc tcattgtttc catccttgat attctggttt tcttgggcat
11101 tctttttggg cttaccatcg ccggctggct gctggtttgg tgtatcagac
11151 tggttttcgc cgcggtattc cgtgcgagtc gaaagactga ccagtctgac
11201 atacagaagg tactttagag atgccatcaa gttatgtcaa ccagatgcca
11251 tccattatgg caagggtttt gggatgcttt ggcacatgaa aattgctacc
11301 atgcttgatg atgtaataca cagtcgtcta atgtctcata tgtctcacca
11351 aggtcgcgag acctggggta gggtgttcac ccagaaggca ttggagaaca
11401 tcggacgaac tcaagttgtg tcacatctcc aacagatagc aggcttggaa
11451 agggaggcgt gcacatatct aatgtctcgg cttcccgcca ttcaggccgc
11501 ttctgcagtg tataatgtaa ccatcaagtt tagcaatgaa accatagcca
11551 tcagctttgg accatcaaac acatccctca cagtagctga gcacctatgg
11601 ctggtgtcaa tgcaatcttc tgtcttttca tctgttgcag cggcatttgc
11651 tttgtggatt gtaatgttac tgcgtctacc caggtctgtc tttggtttcc
11701 tatccatgag acgggtaaga cgcacctaga gttggcccta aatttcacct
11751 tatgtaagat gtgtggcgtg gttgagaatt cttattactc ccaccctttt
11801 tgtgtgactg atgatacttg tgaggagtca tcctcacagt acttggattt
11851 tgacttcccc gatgatgtcc agttgttgtc ctcaatatat ggcacaatcg
11901 ccatcaatgc cctggtgttc gccatacatc aagtcccatc gatgtttggc
11951 aatgtatcag cagtcttctt tagtcacaat tctttgtgtt ataacagcac
12001 cccagtggag cacaatcaga atgtaaccac gtccttggcc atctttgatg
12051 gtgacgtgga aaaatggtat gtgttagagt acattcgacc actcttttca
12101 tcctggttgg tcttgaatgt ctcctacttt ctcaggcgct ccactgccgg
12151 ccgtgctaca cgaaggctgt gagtgttttt aatcatagca acatcccatt
12201 agggaatggt ctgctgatgc atacccaagg gtgtcatatt acacataaaa
12251 aaggaggtga cccatgttac acatggatcg gccaaggtga aggggttgga
12301 attaatttca actacaccgg tgctggacat gaacatgttg ccaacttagt
12351 gaccttggct gcgtgcttaa tacacgcggt tgagctaaag gaaactggat
12401 ttcatccaca attttttaat gtgtctggcc atttggccgt ttgtataaat
12451 tttactgagt atgtgagtca tattcaaaat aaaacctggc atgaagcttt
12501 gaagcttcga ccggcccact ttctttcccc tagtgtagtg aaatggggaa
12551 cggttataac cttggttttg gccatattat tggcaatatg aaatgtttga
12601 agaaattggg cagtggttgg ataccatcac ggttattgcc attttgtttt
12651 attttgtatt ttctctctac cgaaaatgcc tgcgccgcag gcaacagctc
12701 aaccaagaat ttgatctaca acttaacctt gtgtgagctg aatgtgaccg
12751 ggtttcaaca acatttcggt tacgcggtag agacatttgt aatttttcca
12801 gctttgactc acttaatttc cttgaatttt cttaccaccg cccacttgtt
12851 agattttctt tcattgggca ttgtagctgg aggaggctat tggcataaac
12901 agtatgtcat tagctcaata tatgcaagtt gtgcccttct cgccttcatt
12951 ttcttctgct gtagagcagt taggaattgt atgagctgga gatataagtg
13001 caccagattt acaaattttg tccttgatac caaaggaaaa gtctaccgga
13051 accgcagtcc ggttctggtg gagcagcatg gccgagtcat gctacaaggc
13101 cacccaattg aggttaagac cgttgtgctc gatggtgtga aagccgtgcg
13151 ggctaaaacc gtccctgccg aaaaatggga ggcctagaat tttgtgatca
13201 aacttcctgg tatcagatac tgattgcctt tagtttgact tataccccaa
13251 ttgccatcta cagccttaag gtttttcgtg gcactttggc tggtattgta
13301 aatattttta tttttataaa ttgttgtgtt agttttgtgt atttgatgta
13351 ccatcattct gttaccaaca cagttgcgct gtctctcgga gctgttattg
13401 ccctcgtgtg gggcatttac actcttgtca agatagtaaa ctggatggta
13451 ctcagatgcc ggttgtgctt cctaggtaga agttacatcc tagccccacc
13501 cagccacgtg gacacctctg acggacgtca gagcctaacc acatcgtcaa
13551 caaccgcctt tgtggttagg aagccaggta gtacccttgt gaacgggcag
13601 ttggtcccgg actttcaaag actcgtgctt gggggcaaga aggccgtatc
13651 aaaaggagcg gttaaccttt tgaagtatgt ctcaaaataa gaagaaaagc
13701 ggccagaata aaggggcaaa ccagcaactt aatcagttga ttaatgcatt
13751 gcttcgcaat gccggacaga ataaaggaaa ggggcagaaa aagaagaagc
13801 agcccaagct gcacttccct atggcgggac catctgatct ccgccatgtg
13851 atgaccccta atgaggtaca aatgtgtaga tcctcattgg taaccttgtt
13901 caatcaaggt ggtggacagt gtaccttagt tgactccgga gggatcaatt
13951 tcactgtcag tttcatgctt ccaacgcatg ccactgttcg gctaattaat
14001 gcttctgcta attcttctgc ttaagagtta caatgtaagt catgtcagtc
14051 agatgcagcg actcagcctt ttgtaattaa ttgcgatttg gctgggccgg
14101 aatt