Notes on Genus: Quaranjavirus

enveloped spheres or pleomorphic

Type member: Quaranfil virus

Contents

• Members of this Genus
• General Description
• Morphology
• Electron Micrograph
• Genome
• Genus Genomic Organization
• Genome Map
• Type Member Genomic Organization
• All Known Sequences
• Curated Sequences

General Description

The genus Quaranjavirus is one of the genera in the family Orthomyxoviridae. It is named from two of the constituent viruses (which are themselves named from their places of origin), Quaranfil virus and Johnston Atoll virus. The viruses differ from those in most other genera of the family in having insect (tick) vectors and 6 monocistronic genome segments. Distantly related tick-borne viruses with 6 or 7 segments are classifed in the genus Thogotovirus.

Morphology

Virions spherical or pleomorphic, enveloped, 80-120 nm in diameter, with projections about 4-6 nm in diameter and 10-14 nm long.

Genome

Single-stranded negative sense RNA in 6 segments totalling about 11.5 kb. The segments do not have a genome-linked protein (VPg) at their 5'-terminus nor a 3'-polyA tail.

Genus Genomic Organization

There are 6 RNA segments, each of which encodes a single protein in the complementary sense.

Type Member Genomic Organization

There are 6 RNA segments:

• RNA1 (2421 nts) encodes a basic polymerase (PB2) of 84.8 kDa
• RNA2 (2403 nts) encodes an acid polymerase (PBA) of 78.4 kDa
• RNA3 (2386 nts) encodes a basic polymerase (PB1) of 88.2 kDa
• RNA4 (1726 nts) encodes a 59.2 kDa protein of unknown function
• RNA5 (1616 nts) encodes a putative glycoprotein of 57.3 kDa
• RNA6 (900 nts) encodes a 29.5 kDa protein of unknown function